Gliformina tablets 0.25 g

Roman name

Tabulettae Gliformini 0.25 g

The composition and the form of

1 tablet contains metformina hydrochloride 250 mg; Banks in a dark glass of 100 pcs. , in one bundle Bank.

Of drugs

Gipoglikemicescoe. Do glucose disposal muscles, delaying induction carbohydrates in the gut, glukoneogenez down in the liver, increases the sensitivity of peripheral tissues to insulino.

Pharmacokinetics

Absorbed slowly, the material is 50-60%. Easily passes gistogematicalkie barriers and relate to the fabric. Return via the kidneys, mostly in unaltered form.

Farmakodinamika

Reduces sugar content in the blood. It is a significant decrease in body mass index in patients with diabetes suffering from obesity reduces appetite. And lipid and fibrinoliticakimi properties.

Clinical pharmacology

The effect occurs in 4-5 h after administration.

Indications

Diabetes mellitus type II (insulinnezawisimy), especially against the backdrop of obesity (with the poor of metabolic diet and physical load). In combination with insulin : diabetes mellitus type I (insulinzawisimy) insulinrezistennetary diabetes mellitus, diabetes and resistance to sulfonylureas derivatives.

Contraindications

Complete cessation of endogenous secreting insulin diabetes type II, albuminurija motivated nefropatii diabetes, liver failure, diabetic angiopatia provision for the development of inflammation, infectious diseases, gangrene limbs, pregnancy.

Side-Effects

Metal taste in the mouth, gastrointestinal disorders, increasing the concentration of vitamin B_12 (to within a few years), allergic skin reactions.

Dosing and Administration

Inside, during or immediately after a meal. Dose set individually. Initial dose-table 1-2. once a day (morning) and the dose gradually increased to 2-3 table. 2-3 times a day. Supporting dose-table 1-2. 2-3 times a day.

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