Reklid

Roman name

Reclide

Pharmacokinetics

Quickly and completely absorbed from the digestive tract. C_max is 2-4 hours Linking plasma protein is 94.2%. The allocation is about 25 litres. Metabolised in the liver, kidneys excreted. T_1/2-12 p.m.

Farmakodinamika

Restores physiological level secreting insulin (normalizes early rush and reduces peak postprandialny io), shortens the time to eat the food before its secretions. Decreases adhesion and agregatia platelets, inhibits growth pristenerngo ankle increases fibrinoliticescuu activity of the vascular wall permeability normalizes receptacles and hinders the development mikrotromboza. Wrinkles develop diabetic retinopathy at neproliferativoy stage reduces proteinuriu reduces body weight in fat patients.

Indications

Insulinnezawisimy diabetes (type II), including : oslojnenny angiopatiei.

Pregnancy and lactation

Contraindicated in pregnancy. At the time of treatment should stop breastfeeding.

Contraindications

Hypersensitivity, insulinzawisimy diabetes mellitus (type I), Youth diabetes, ketoacidosis, diabetic coma and precoma, severe kidney or liver failure, pregnancy, breast-feeding.

Side-Effects

Hypoglycaemia, diarrhoea disorders, reversible hematologic violations allergic reactions.

Specific guidance

Food increases the risk of gipoglikemii. It should not be used in conjunction with drug miconazole.

Patient interaction

Effect increase sulfanilamida, fenilbutazon, salicilata, klofibrat, indirect combined, etanolsodergaszczye drugs, MAO inhibitors, theofillin, caffeine; Weaken - glukokortikoida (including forms for the exterior), dioretiki (furosemide, etakrinova acid derivatives tiazida) estrogena, progestagena, difenin, rifampicin, barbiturates.

Storage conditions

List B. In the dark place at a temperature of no higher than 25 ° C

Shelf life

The registration

011468/01-1999

The drug forms

White or almost white round tablets flat lead from the edges, on the same side vdavleno "RECLIDE" at the other "80".

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