Directory → Metaboliki → Lipid means → Other means gipolipidemicakie → Chenodeoxycholic acid
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Chenodeoxycholic acidChemical name(3альфа,5бета,7альфа)-3,7- Дигидроксихолан-24-ова я acidGrossC24-H40-O4CharacteristicsWhite or slightly yellow powder. Nerastvorim in water.Of drugsThe drugs-holelitoliticescoe, jelchegonnoe, гипохолестеринемичес кое. Fermentativei stops synthesis of cholesterol in the liver, reducing its content in bile and leads to the gradual dissolution holesterinovykh stones. Almost completely absorbed from the intestine. The liver kongugiruet with amino acids, in secretiruetsa elixirs and again singled out intestine, which in part reabsorbiruetsa (rest of the message with faeces).IndicationsHolesterinove jelchne stones stored in the gall bladder.ContraindicationsObezazwestvljenne jelchne stones of the bowel syndrome malabsorbtion, jelcnaya kolica, pathology psoriasis ways and pancreas, chronic hepatitis and cirrhosis, pregnancy.Side-EffectsNausea, pain in the area epigastralna, diarrhoea, skin rashes and skin.Patient interactionDo antidiabetikov effect. Therapeutic activity reduces antatsida, holestiramin.Dosing and AdministrationInside, at the rate of 15 mg / kg / day (1 / 3 hours and 2 / 3 of the evening); Maximum daily intake of 1.5 g. The course of treatment is up to 1 year.See also |
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