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Henohol

See also Chenodeoxycholic acid

Roman name

Henohol

The composition and the form of

1 capsule contains henodeauxiholeva acid 250 mg; in a carton blisters 7 to 8 pcs.

Of drugs

Gipoholesterinemicescoe, holelitoliticescoe. Oppressing education, and the cholesterol from jelchew contributes to the gradual dissolution of stones.

Pharmacokinetics

Almost completely rezorbiruetsa of blood through passive diffusion in the brain and the gut rezorbtion active in the face of atherosclerosis. Henodeauxiholower acid in the liver with kongugiruet glitzinom and taurinom form хенодеоксихолилглици н henodeauxiholiltaurin and, in the form of assets or their salts with sodium or potassium is the jelchew clearance in the bowel. A small portion is allocated to the calf and the other through suicide vorotnuu returned to the liver, where dekongugiruetsa. Bacterial enzymes in the gut degidrauxiliruut kongugirovannuu henodeauxiholevu acid in litojolevu, which also reabsorbiruetsa hydrolyses and in the liver.

Indications

Holesterinove (rentgenoprosracne) jelchne stones diameter less than 20 mm (when saved as gall bladder).

Contraindications

Neholesterinove jelchne stones holetsistit jelchnokamenna the disease, acute and chronic hepatitis, gastric ulcers and duodenal ulcers; Inflammatory diseases of the gastrointestinal tract; Malabsorbtion syndrome, severe kidney or liver failure, pregnancy.

Side-Effects

Diarrhoea; Pechenocnae cramps (Migrating stones); Transaminaz increase in the blood.

Precautions

In transaminaz increase in the blood daily dose reduction of 31 caps. , For the four weeks are not normal, no treatment. Constant monitoring of the liver (pechenocnae samples). During therapy to women contraception.

Dosing and Administration

Inside, 15-18 mg / kg / day in 3 admission : morning and afternoon to 1 caps. , In the evening, two caps. For a period of not less than six months (up to 1-2 years). If, after six months there has been erosion of the stones come out; If the treatment is effective, it still (prevention lithogenesis re) assignment to 1 caps. per day for 1 month and then every third month.

Storage conditions

caps. : List B.

Shelf life

caps. : 3 and

All products of this group

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