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Lipanor

See also Ciprofibrate

Roman name

Lipanor

The composition and the form of

1 capsule contains ciprofibrata 100 mg; blistere in 10 pcs. , in box 3 blisters.

Pharmacokinetics

Quickly and almost completely absorbed. C_max after taking prandial achieved after one hour with a drug after eating through 2-3 hours; Is associated with plasma proteins, T_1/2 - 88.6 ± 11.5 hours

Farmakodinamika

Increases LPVP level. Increases the diet to lower cholesterol engineers, LPONP and triglycerides.

Indications

Primary giperlipidemia (giperholesterinemia, gipertriglitzeridemia or combined forms of type IIa, IIb, III, IV).

Contraindications

Severe liver or kidney failure, pregnancy, breast-feeding (at the end of treatment).

Side-Effects

Headache, dizziness, fatigue, weakness, drowsiness, nausea, vomiting, diarrhoea, neuralgia, changing functional liver samples holetaz, zitoliz, mialgia, miopatia (including myositis and rabdomioliz), impotence, alopecia, pnevmonit, pulmonary fibrosis, skin rashes, urticaria, skin.

Patient interaction

Do effect of oral anticoagulants. Inhibitors гидроксиметилглутари лкоэнзим-А-редуктазы or other fibrata increased risk of rabdomioliza and mioglobinurii.

Precautions

If mialgii, muscle pain to the touch or muscle weakness should immediately undertake the activity CPK, and, in case of detection of myo - or significantly higher levels of CPK, to stop treatment. It regularly monitor pechenocnae functional tests, while maintaining the activity of liver enzymes that therapy. Prior to the reception should be deleted gipotireoidizm, a risk factor of myo-and can cause secondary dislipidemia. The development increases myo any clinical situation occurring with gipoalbuminemiei, incl. argued syndrome.

Dosing and Administration

Inside, adults and 1 caps. (100 mg) a day; at a moderate kidney failure, 100 mg every other day.

Storage conditions

B. List in a dry place so that the temperature does not exceed 25 ° C

Shelf life

3 years

The registration

012021/01-2000

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