Directory → Metaboliki → Lipid means → Statins → Lipobay
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LipobaySee also CerivastatinRoman nameLipobayThe composition and the form of1 tablet coated liner contains sodium tseriwastatina 0.2 or 0.4 mg; blistere in 14 pcs. , in box 2 blisters.FarmakodinamikaThere cells in the liver, Intracytoplasmic lowers cholesterol and enables engineers sensitive receptors on the surface of cells. Increases taking cells cholesterol quantum of flow and reduces the total cholesterol and cholesterol finds in the blood.Clinical pharmacologyEffects develops over two weeks and reaches its peak after one month. Productivity remains for the duration of therapy.IndicationsPrimary hyperlipoproteinemy type IIA and IIB, giperholesterinemia inefficiencies in the diet.Pregnancy and lactationContraindicated in pregnancy. At the time of breast-feeding treatment should be discontinued.ContraindicationsHypersensitivity, violations of the liver, permanent increase in transaminaz in plasma unclear etiology, non-implementation of reliable contraception for women of child-bearing age, pregnancy, child.Side-EffectsGrippopodobnyy syndrome, headache, myalgia, sinusit, cough, pain in the joints, back pain, muscle aches, sleep disturbance.Patient interactionImproving risk of myo ciclosporin, derivatives fibroeva and nicotinic acid, erythromycin and antifungals azolovy stimulants. Suction reduces ion-exchange resins (kolestiramin).OverdosingTreatment : a simptomaticescuu therapy. Specific antidotes to the drug Lipobay does not exist. Haemodialysis ineffective because of the high tseriwastatina connection with the squirrels, but can be applied transmembrannoe division plasma proteins.PrecautionsBefore treatment should be deleted secondary NCEP, the functional pechenocnae samples and periodically repeat them. When the blood levels of AST and ALT (more than three times), CPK (10 or more times), with suspected or apparent myo reception should be discontinued. Be wary appoint patients with liver diseases in history, as well as people in a large number of drug Alkogol.preparat temporarily cancelled for conditions predisposing to the development of renal failure due to rabdomiolizom. With caution, and under the close supervision of medical appointed to the human kidney (Cl creatinine less than 30 ml / min). The treatment should observe diet conducive to lower cholesterol levels.Dosing and AdministrationInside, every day, in the evening or at night, regardless of meals; Initial dose-0.2-0.4 mg / sut. The maximum dose of 0.8 mg once a day. The patient must comply with the standard holesterinsnijatuyu diet.Storage conditionsList B. In the dark place at a temperature of no higher than 30 ° CShelf life3 yearsThe registration009,695 (Ann.2002) |
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