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Liprimar

See also Atorvastatin

Roman name

Liprimar

Farmakodinamika

Reduces the total cholesterol, cholesterol engineers, apolipoprotein B, triglycerides.

Clinical pharmacology

Most of the patients seen at the dose of 10 mg / day for 2 weeks, and the maximum effect is to 4 weeks and maintained for a period of time. In the same dose concentration in the plasma significantly increased in patients with alcoholic liver cirrhosis.

Indications

Primary giperholesterinemia combined (mixed) giperlipidemia, heterosexual and gomozigotnaya giperholesterinemia family (in addition to the diet).

Pregnancy and lactation

Contraindicated in pregnancy. At the time of treatment should stop breastfeeding.

Contraindications

Hypersensitivity, liver disease in the acute phase increased whey transaminaz (more than three times) ambiguous genesis, pregnancy, breast-feeding, reproductive age in women who do not comply with adequate contraception.

Side-Effects

Headache, insomnia, nausea, neuralgia, aches, pain in the abdomen, constipation or diarrhoea, mialgia, man.

Precautions

Before admission to a standard гипохолестеринемичес кую diet to be followed and at the time of treatment. To use caution in patients with history of alcohol abuse and / or suffering from liver disease, it should be to keep its functions : if the level of AST and ALT (more than three times) that reduces dose or withdrawal from the market. Last necessarily in the development of myo (or even suspected it).

Storage conditions

List B. At temperatures below 25 ° C

Shelf life

3 years

The registration

014014/01

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