Directory → Metaboliki → Lipid means → Statins → Lovastatin
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LovastatinSee also LovastatinRoman nameLovastatinOf drugsThe lovastatina linked to the inhibition of the biosynthesis of (putting education in the body) cholesterol.Shelf lifesubst. : 2 grams.Indications for useAssign lovastatin patients with primary giperholesterinemiei (high cholesterol in the blood), accompanied by a high-certainty in the absence of therapeutic effect of diet, as well as patients with a combination of NCEP (high cholesterol) and triglitzeridemy (elevated triglyceride content in the blood).Dosing and AdministrationAdults product shall, starting with the usual dose of 0.04 g (40 mg) once a day during dinner (synthesis of cholesterol takes place mainly at night). In light NCEP forms can be made smaller doses (20 mg / day). A patient must comply with the diet. The effect develops in about two weeks. (maximum impact through 4-6 weeks). . The inefficiency of the drug dose increases (at intervals of no less than 4 weeks). To 80 mg in 1 or 2-reception at the luncheon and dinner. By reducing the overall level of cholesterol in the blood plasma than 140 sales ml (3.6 mol / l) lovastina dose should be reduced. The lack of kidney appoint not more than 20 mg per day.Side-EffectsThe drug is usually well tolerated. There may be changes of the liver increased transaminaz level in the serum, muscle pain, myo (known as muscle disease characterized by muscle weakness and the decline in active movements), neuralgia (eating disorders), headache, skin rash.ContraindicationsContraindicated in pregnancy and breastfeeding, acute liver diseases and steady increase trasaminaz in plasma. Children agent is not appointed.Form ofAnswers to 0.1 g, 0.2 g or 0.4 g.Storage conditionsList B. In a cool, the dark place at room temperature (up to 30 ° C). |
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