Vero-simwastatin

Roman name

Vero-simvastatin

The composition and the form of

1 tablet contains simwastatina 10, or 20 mg; in a contour acheikova packing 10 pcs. , in a cardboard unit 1, or 3 packaging.

Of drugs

Gipolipidemicescoe. Limit cholesterol synthesis in the early stages, and the blocks 3-гидрокси-3-метилглют��рилкоэнзима A reduktazu.

Indications

Disease, arteriosclerosis cerebrovascular, giperholesterinemia.

Pregnancy and lactation

Contraindicated in pregnancy. At the time of treatment should stop breastfeeding.

Contraindications

Гиперчувствительност ь (including any of the components of the drug), liver disease (the active phase) increased transaminaz plasma unclear etiology, pregnancy, breast-feeding.

Side-Effects

From the nervous system and sensory organs : headache, dizziness, fatigue, paresthesia, peripheral Neiropatia.so part of the intestine : diarrhoea phenomenon pain in the abdomen, nausea, vomiting, flatulence, diarrhea, constipation, hepatitis, jaundice, Pankreatit.so the musculoskeletal system : lung muscles, mialgia, miopatia, rabdomioliz, polimialgia Medicine, arthritis, Artralgia.so the circulatory system and blood (blood, gemostaz) : anaemia, vasculit, improving Monday, thrombocytopenia, �озинофилия.Аллергиче ские reactions : angioneuroticeski swelling, volchanochnopodobnyy syndrome, skin rashes, itching, urticaria, Fotosencibilizace.prochie : alopecia, fever, hyperemia skin, shortness of breath, malaise, swelling angioneuroticeski, deviations in laboratory performance (more transaminaz, alkaline phosphatase, gamma-glutamiltranspeptidaza, CPK skeletal muscles, changes in the functional liver samples).

Precautions

Before treatment is recommended (and then periodically repeat), a study of the liver. When the transaminaz more than three times the drug should be lifted. Be wary designate patients who misuse alcohol and / or have a history of liver disease.

Dosing and Administration

Before and during the treatment must be respected gipoholesterinovu diet. Inside, in the initial dose of 10 mg once, in the evening; In the light or moderate extent NCEP initial dose of 5 mg; If necessary dose gradually increased at intervals of four weeks. The family gomozigotna NCEP daily dose of 40 mg once, in the evening or 80 mg / day (separated by 3 receiving 20 mg morning, 20 mg a day, 40 mg evening). In IBS initial dose of 20 mg, once, in the evening; If necessary, gradually increased at intervals of 4 weeks to 80 mg.

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