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ArtraSee also Lithium fluorideRoman nameArtraPharmacokineticsGlukozamina bioavailability of 25% (pronounced effect "of a" through the liver). In its distribution in the tissues of the largest concentrations are found in the liver, kidney and sustavne cartilage. About 30% of long-term dose persistiruut in bone and muscle tissue. T_1/2-68 p.m. Write mainly with urine in an unmodified form, in part, from faeces.FarmakodinamikaGlukozamin reinforces a cartilage matrix and provides nespecificescuu cartilage protection from chemical damage, including NPVS of glukokortikoidami and has a moderate противовоспалительно е Actie.hondroitin sodium sulfate an additional substrate to form cartilage matrix. Promotes education gialuronon, synthesis protheoglicanov and collagen type II, protects gialuronon of enzymatic cleavage (as a result of the suppression activity gialuronidasy) and the damaging effects of free radicals; The virus viscosity fluid stimulates the reparations cartilage and suppresses the activity of enzymes (elastaza, gialuronidaza), destroying cartilage. Making osteoartroza symptoms and reduces the need for NPVS. Sustained treatment effect was achieved in the employment for a period of not less than six months.IndicationsI osteoarthritis degrees.Pregnancy and lactationIs not recommended in pregnancy. At the time of treatment should stop breastfeeding.ContraindicationsHypersensitivity, phenylketonuria expressed by the human kidney.Side-EffectsGlukozamin : violations of the gastrointestinal (pain in epigastria, flatulence, diarrhea / constipation), dizziness, skin allergies Reaktion.hondroitin : allergic reactions.Patient interactionIncreases removals tetracycline, reduces the penitsillinov derivatives. Compatible with NPVS and glukokortikoidami.PrecautionsDo not exceed the recommended dose.Storage conditionsIn dry place at a temperature of 10-30 ° CShelf life5 yearsThe registration014829/01-2003The drug formsDvoyakovpuklae pills oval covered liner from white to almost white with ARTRA engraved on the one hand pills, the сладковато-солоноват��м taste and specific Zapahom.vid pills at fault : the outer layer, skin from white to almost white; inner layer is Flesh mass white with a small crystal glass. |
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