Ipriflavone

Chemical name

7-(1-Метилэтокси)-3-фени��-4H-1-бензопиран-4-он

Gross

C18-H16-O3

Of drugs

The drugs-ingibirutee bone resorption. Improves metabolism of bone tissue, reduces its resorption. In the blood of 95% is associated with malnutrition. T_1/2 - 9-10 hours Biotransformiroetsa in the liver with the formation of active metabolites.

Indications

Two primary (post, senilny) and the secondary (post in glukokortikoidami therapy).

Contraindications

Hypersensitivity, increased ulcers stomach and duodenal ulcers, oppression blood (eritro-, leiko- and thrombocytopenia), severe liver disease and kidney failure, pregnancy, child.

Side-Effects

Neuralgia, headache, dizziness, weakness, sputannosti consciousness allergic reactions.

Specific guidance

When the consumption of food containing calcium should appoint him more, 1 g / day.

Patient interaction

Calzitonin, estrogena (with osteoporosis related to scarcity) increase efficiency.

Precautions

Be wary combine with coumarin derivatives and NPVS. Breastfeeding women at the time of treatment should stop breastfeeding. In a long-term need for systematic control picture peripheral blood, liver and kidneys, the drugs hidden in the blood (in the first 3 months of therapy each month, then once every three months). Patients ulcers stomach and duodenal ulcers in history, as well as diseases of liver and kidney failure in the appointment of the drug should be more frequent clinical and laboratory monitoring.

Dosing and Administration

Inside, the food on the table in January. three times a day. The course of 4-10 weeks to 12 months.

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