Tevanat

Roman name

Tevanate

Characteristics

Refers to a group aminobifosfonatov-synthetic analogs pirofosfata, swyazawategosa gidroxiapathitom with, as part of the bone.

Indications

Prevention and treatment of osteoporosis posmenopauznogo women and senilland osteoporosis in men. Steroidnyi osteoporosis caused by the use of corticosteroid (treatment). More Pejeta (bones). Gipercalziemia due to malignant neoplasms.

Pregnancy and lactation

Contraindicated in pregnancy. At the time of treatment should stop breastfeeding.

Contraindications

Hypersensitivity, gipocalziemia, strictora ahalazii and oesophagus and other conditions leading to the slowing of food pishchevodu; Failure patient stand or sit for 30 minutes, severe renal insufficiency (Cl creatinine less than 35 ml / min), gross violations of mineral exchange's age, pregnancy, Lactace.s period caution, with the blood disease in the phase of deterioration (disfagia, ezofagit, gastritis, duodenit, saying disease stomach and duodenal ulcers), the lack of vitamin D.

Side-Effects

Local irritation of mucous membrane of upper gastrointestinal divisions, izgyazwlenia mucous membrane duodenal ulcer, pain in the abdomen, diarrhoea disorders, constipation, diarrhea, bloating, nausea, vomiting, disfagia, izgyazwlenia mucous membrane oesophagus, stomach distonia, melena, engine acid stomach contents in the esophagus, bone, muscle and joint aches, headache pain. Seldom-erythema, ezofagit, erosion mucous membrane oesophagus, pitting mucous membrane mouth and zeva (cut), stomach and duodenal ulcers, the reactions гиперчувствительност и (skin rash, swelling), uveit, sclerit.

Specific guidance

Combined with the use of estrogen drugs (but not simultaneous) is not accompanied by changes in their actions and the development of spin-off Effectov.priem PREDNISOLONE into healthy volunteers was not clinically significant changes bioavailability alendronova Kislota.sleduet be particularly attentive to any signs of adverse events in the field of nutrition. In developing disfagii, pain when swallowing, pain in the sternum or izjogi, discontinue use of the drug and to Vrachu.patientam with gipocalziemiei prior to the start of treatment should be corregirutuyu therapy of mineral exchange, including calzitriola deficit. The treatment may occur asymptomatic decrease in the calcium concentration in the serum and phosphate (to be borne in mind when treating patients receiving glukokortikoida). In this case, you should ensure adequate supply of calcium and vitamin D from their diet or in the form of drugs.

Patient interaction

Together with the admission of drugs calcium antatidami reduced absorption alendronova Kislota.npvs increase adverse action alendronova acid.

Precautions

We have to take medication at night or before morning rise to the Posteli.neobhodimo make a break of at least 30 minutes between meals alendronova acid, and all other oral PP.

Storage conditions

List B. The temperature is not above 30 ° C

Shelf life

3 years

The registration

(OL)

The drug forms

White or almost white dvoyakovpuklae pills without risks.

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