Ferrous fumarate

Chemical name

Iron (II) boutendioat salt (1:1)

Gross

C4-H2-Fe-O4

Of drugs

The drugs-gemopoeticescoe, eritropoeticescoe, protivoanemicescoe. Fills in the body iron deficiency required for the synthesis of hemoglobin, etc. globinovykh ферментов.Характериз��ется biodostupnostthew high because dwuhvalentnoe iron (zakisnoe) is readily absorbed and fumaric acid reinforces the skin. C_max achieved through 6700 after the reception. T_1/2 about 12 hours When transmitted anemiah receiving 350 mg once a day is the minimum effective dose of iron. This increases the level of hemoglobin (and iron) in the serum, the number of cells; All hematologic and clinical symptoms of anemia regressed in 3-4 weeks of treatment.

Indications

Blindness anaemia : postgemorragicakie menorragii, chronic krovopoteri in blood, etc.); Increased demand for iron (pregnancy, lactation, a period of intense growth and sexual maturation, especially among girls), the treatment and prevention; Insufficient supply of iron ingestion and violating the intake (chronic diarrhoea morbidity invasion); iron deficiency in the elde 10f8 rly and senile age (as a trial treatment).

Contraindications

Gemoliticaskie (hereditary and acquired), etc. anemia not related to iron deficiency, hemochromatosis, a disease hospital of stomach and duodenal ulcers in the phase of deterioration, inflammatory bowel disease (ulcerative disease, Baby Ulcerative Colitis).

Side-Effects

Anorexia, metallic taste in the mouth, nausea, vomiting, obstipation, diarrhoea.

Patient interaction

Violate (mutually) lost antibiotics tetratziklinovogo stimulants. Almagel salt and magnesium affect absorption from the bowel.

Overdosing

Symptoms : nausea, pain in epigastria, vomiting with blood, diarrhea, dizziness, weakness, sputannosti consciousness akrozianoz, demotion AD weak Puls.lechenie : stimulation vomiting, stomach wash (in the early stages), the appointment of milk from Egg protein; A specific (nomination inwards and dropped deferoksamina), and symptomatic therapy.

Precautions

There is a need for regular monitoring of blood : a sign of the effectiveness of treatment is to increase the number of reticulocytes in 7-10-i day from the start and the normalization of haemoglobin levels in 3-4 (sometimes 6-8) weeks. When bad endurance shown reducing dose reception drug at the time of delivery, as well as a short break from treatment.

Dosing and Administration

Inside, erh, 30 minutes before breakfast, adults and children over 12 years of age-1 caps. per day or 10 ml of suspension 3-4 times daily for a period of 6 to 12 weeks. If the dose effect can be enhanced by one caps. twice a day. Admission to and after picture of the normalization of blood. The saturation of therapy at least 1-1.5 months. For children up to two years to 5 ml suspension once a day, 2-6 years, twice a day, over six years, three to four times a day. Suspension are in the intervals between meals, combination with water (but not necessarily).

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