Kali-normin

Roman name

Kalium-normin

Characteristics

Light 4.2.2 on both sides diskobraznae pill white with a marble figure in gorkovatam taste odourless. Color tablets at the turning point of the white.

Pharmacokinetics

Once inside easily and almost as many passively absorbed (absorption - 70%), because the concentration (as food, and freed from the drug form) in proswete small bowel than in the blood. Of retard tablets gradually and slowly released throughout the digestive tract. In face and large intestine K ^ + is the clearance cancer on the basis of risk sharing with Na ^ + and is the jelchew (10%). The K ^ + in the body lasts about eight hours from the time of admission. T_1/2 Phase removals, 1.31 hours; Time of the release tablets retard-6 pm

Farmakodinamika

Potassium reduces anxiety and conductivity attack, it weakens the toxic cardiac glycosides, respecting their positive inotroponoe Actie.v small doses K ^ + extends coronary vessels, in the big-big. Participates in the process of nerve impulses. Activates many zitoplazmaticalkie enzymes regulates Intracytoplasmic KISR pressure synthesis of protein, amino acid transport. Improves reduce skeletal muscle in muscular dystrophy, myasthenia.

Indications

Prevention and treatment gipokaliemii different genesis, incl. by the various states and diseases (vomiting, diarrhoea), and from drug (dioretiki, glukokorticosteroida, heart glycosides).

Pregnancy and lactation

If necessary, the use of pregnancy should compare the expected benefit to the mother and the potential risk to the fetus. At the time of treatment should stop breastfeeding.

Contraindications

Hypersensitivity to the drug, giperkaliemia full AV blockade napochechnikovaya failure, chronic renal insufficiency, concomitant therapy kalisberegatmi dioretikami, metabolic disorders (disorders, gipovolemia with giponatriemiei) erosivno-azwenne shock syndrome, pregnancy, breast-feeding, age and 18 years of age.

Specific guidance

During the period of treatment, there is a need to control the content of K ^ + in the serum, ECG, KHS. Safety and effectiveness of the potassium chloride in children have not been established. Diet rich in sodium chloride removal increases K ^ + from the body. It should be borne in mind that giperkaliemia leading fatal, can develop quickly and proceed asymptomatic.

Patient interaction

Kalisberegate dioretiki, drugs, potassium ACE inhibitors, NPVS increase the risk of developing giperkaliemii. Decreases side effects of cardiac glycosides. Do the hinidina, side effects dizopiramida.

Dosing and Administration

Inside. Dose set individually depending on the disease and the concentration of potassium in the blood plasma. At 1-2 g / day (per potassium chloride), a dose increase of up to 6 g / sut.

Storage conditions

In dry place at a temperature of 15-30 ° C

Shelf life

3 years

The registration

015285/01

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