Magnesium orotate

Gross

C10-H6-Mg-N4-O8

Of drugs

Drugs, the skin, complementary deficit magnesium and orotova acid antiaritmicescoe, antiagregatine. Magnesium is involved in transport, storage and disposal of energy, the synthesis of protein and nucleic acids, a muthondrialnah processes. Is kofactorom many enzymatic reactions : hydrolysis and transfer of phosphate groups of Na ^ + K ^ + -atfaznogo, Ca ^ 2 + -atfaznogo and proton pumps. Controls balance intracellular potassium. In acute myocardial infarct magnesium offsets the systemic vascular resistance increases coronary blood, warns koronarospazm, serves as cardioprotector by removing vnutricletocny deficit is not only magnesium, and potassium phosphate (at the same time decreasing the calcium and sodium), reducyruet a heart attack and the severity of heart failure. Impact synthesis tromboksana B_2 and oppressing agregatia nine, including тромбининдуцированну ю. Orotovaya acid metabolite capitalist involved in the construction of pirimidinovykh grounds of the nucleic acids. Improves regeneration processes, stimulates the synthesis of proteins sokratitionah attack contributes to cellular magnesium recycling and the use of its effects.

Indications

Rhythm irregularities, including jeludockove keep in digitalisna intoxication acute myocardial infarction (prevention arrhythmias), stenocardia, including vazospastical, arteriit, arteriosclerosis, dislipoproteidemia deficit magnesium caused increased requirements (pregnancy and lactation), a decrease of ingestion and digestion, increased breeding (chronic diarrhea, violations of the kidney giperaldosteronizm, gipercalziemia, Ray, an acute BCC, gipoparatireoz, glukozuria, treatment of diabetic insulin ketoatsidoza), alcoholism, including withdrawal syndrome, cachexia, low protein content in the diet and low-calorie food.

Contraindications

Violations of kidney disease filter (phosphate and magnievo-calzieve concrements), sinoatrialnaya and AV blockade.

Side-Effects

Diarrhoea.

Patient interaction

Decreases iron absorption, tetracycline, sodium fluoride. Decreases of magnesium deficiency and the risk of related complications in the admission dioretikov, aminoglikozidov, tsisplatina, cyclosporine, amfoteritina, pentamidine, methotrexate, laxatives.

Precautions

When treating drugs iron, tetracycline and sodium fluoride, magnesium reception orotata be delayed by at least 2 hours If you have signs of intestinal dispepsia (unstable chair, diarrhoea) dose should be reduced.

Dosing and Administration

Inside, squeezed a small amount of water, 2 table. 3 times / day for 1 week and then 2-3 table. daily, the duration of not less than six weeks. The prolonged use.

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