Etidronic acid

Chemical name

(1-Гидроксиэтилиден)би с[фосфоновая acid]

Gross

C2-H8-O7-P2

Of drugs

The drugs-gipocalziemicescoe governing calzi-fosfornyi exchange, stimulating osteogenesis, nefrolitoliticescoe. She is an active compleksonom. Oppressing normal and pathological bone resorption reduces tumour bone, reduces the number and activity osteoclastov. Prevents christalloobrazovanie and growth of crystals in the urinary tract. After intake of a well-absorbed. T_1/2 about six hours Not biotransformiroetsa. Excreted kidneys.

Indications

Gipercalziemia in neoplasticeskih processes gipervitaminoz D giperparatireoz, osteoporosis, a disease anesthetic.

Contraindications

Violation of the kidney gipocalziemia, pregnancy.

Side-Effects

Metal taste in the mouth, a breach of a kidney disorder touch.

Dosing and Administration

In / in the 7.5 mg / kg per day; Throw in 250 ml 0.9% solution of sodium chloride, infuziruut within 2 hours The course of treatment is 3-7 days. Inside, 20 mg / kg / day for 30 days.

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