Baralgin m

Roman name

Baralgin # M

The composition and the form of

1 ml solution for injection contains metamizola sodium 500 mg; Injection in 5 ml, 5 box ampul.1 tablet-500 mg; blistere in 10 pcs. , in box 10 blisters.

Of drugs

Analgezirutee, skin, cough, противовоспалительно е. Does ziklooksigenzu and reduces synthesis of GHGs.

Pharmacokinetics

Once inside hydrolyses in autism education metabolita active - 4-метиламиноантипирин а (4-MMA), which is absorbed in the liver in 4-aminoantipirin (4-AA), as well as pharmacologically inactive metabolites. After intake of 1 g metamizola 58 4-MMA%, and 48% 4-AA contact with blood plasma proteins. Effective therapeutic concentration in plasma 4-MMA achieved through 20-40 minutes, C_max-in 2 hours

Indications

Pain syndrome weak and the average intensity (headache, dental pain, neuralgia, pain and disease, atherosclerosis, arthritis, menalgii), cramps smooth muscles (renal kolica, jelcnaya kolica, kolica coli), the feverish state of инфекционно-воспалит��льных diseases (in a combination therapy).

Pregnancy and lactation

Contraindicated in the I and III trimestrah pregnancy. Application in the second trimester only for strict medical reasons. Breast-feeding counter within 48 h after administration Baralgina M.

Contraindications

Гиперчувствительност ь to pirazolonam (incl. metamizolizopropilaminofenazonu, propifenazonu and fenazonsoderjasim means fenilbutazonu). Acute hepatic porphyria, congenital deficit глюкозо-6-фосфатдегид��огеназы.

Side-Effects

Agranulozitos, lakopenia, thrombocytopenia, plummeting AD passing of a kidney (oliguria or anuria, proteinurija) intersticialny jade, and the allergic reaction immunopatologicakie (urticarnae skin rash, eyelids, nose shells in the area chair; Syndrome Stevens-Johnson, Laiella syndrome, anaphylactic shock).

Specific guidance

We confuse one sprite with other drugs. Return with the urine of a biotransformation products may cause red staining of urine (clinical significance is not lost, and after the abolition).

Patient interaction

Impact zefalosporina concentration in the blood, increases the effect of alcohol.

Precautions

It is a great deal of caution in arterial hypotonia (AD sistolicescoe below 100 mm Hg); In situations characterized by unstable performance system hemodynamics (acute myocardial infarction, multiple trauma from the shock); In patients with the history of painting peripheral blood (for example, receiving cytotoxic means), or the reaction of hypersensitivity Drugs (food, preservatives, fur, paint for hair), suffering from bronchial asthma and / or chronic �нфекционно-воспалите льными diseases of the respiratory organs especially sensitive to any and NPVS �нальгетикам-антипире тикам (threat of bronchial asthma and shock); baby the first 3 months of life or weighing less than 5 kg (increased risk of functional kidney). Not recommended combined with drugs that cause reactions intolerances (rentgencontrastnye means plazmozameshchate solutions penicillin). The sudden deterioration of the general condition of the patient (temperature, inflammation of mucous membranes of the mouth, nose and pharynx, the EMAS) should be lifted immediately reception. If anaphylacticski shock due to the on / in (slow) 0.1% epinephrine solution (if necessary re-intervals of 15-30 minutes), then glukokortikoid, antihistamines funds for the replacement of blood IVL, massage heart.

Dosing and Administration

In / in, in / m. For adults and adolescents over 15 years single dose of 2-5 ml (in / in or / m), a daily dose of up to 10 ml. In / in a single dose exceeding 2 ml (1 g), perhaps only after a careful placement of testimony. For children and babies daily dose set taking into account body mass index (infants 5-8 kg 0.1-0.2 ml / m; Children 9-15 kg to 0.2-0.5 ml / in or / m; Children 16-23 kg 0.3-0.8 ml / in or / m; Children 24-30 kg - 0.4 ml / in or / m; 31-45 kg-0.5-1.5 ml / in or / m; 46-53 kg 0.8-1.8 ml / in or / m / in a drug should be slowly (1 ml for 1 min), in the patient and the rest under the control of AD curves and respiration rate. Injecting solution must be heated Tela.vnutri, adults on the 500 mg four times a day. The maximum single dose of 1 g daily-3 and

Storage conditions

r-r d / in. : List B. In the dark place at a temperature of 25 ° Ctabl. : List B. In the dark place at a temperature of 25 ° C

Shelf life

r-r d / in. : 4 g.tabl. : 3 and

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