Amitriptilin-ferein

Roman name

Amitritlin-ferein

The composition and the form of

1 tablet, film coated liner contains amitriptilina hydrochloride 25 mg; in the plastic vial 50 pc. , in a cardboard bundle one bottle.

Of drugs

Antidepressive, anxiolytic.

Indications

Маниакально-депресси��ный psychosis (depressive phase), depression (including in childhood), mixed emotional disorders and conduct child enourez (except suffer from bladder), psychogenic anorexia, chronic pain syndrome.

Pregnancy and lactation

In the first trimester of pregnancy with caution.

Contraindications

Hypersensitivity recently moved myocardial infarction, тревожно-параноидаль��ый syndrome (to suicide), zakratougolnaya glaucoma, paralysis occlusion bowel disease, epilepsy, pilorostenoz, Denmark prostate cancer, heart amidst tachycardia, uncontrolled arterial hypertension, a disease hospital stomach and duodenal ulcers, breast feeding, child age to 7 years.

Side-Effects

From the nervous system and sensory organs : drowsiness, disorientation, agitation psychosis, (usually with a big dose older patients); Hand tremor; Sometimes fatigue, dizziness, paresis ccomodation, drugs, ekstrapiramidnye Rasstroistva.so the circulatory system and blood (blood, gemostaz) : sometimes tachycardia, ortostatical gipotenzia, cardiotoksicescoe act Krovetvorenia.prochie violation : dryness and kislo-gorki taste in the mouth, dry nasal mucous membrane, and sometimes urine retention, low potency and libido, ginekomastia, galactorea, increased sweating, skin allergies rarely failure of the liver.

Patient interaction

Do (synergy), the other antidepressants. Ters and gipotenzivnuu protivosudorojnuu activity other products increases, antiholinergicescuu (possible paralysis intestinal occlusion). Inductive mikrosomalnogo oxidation - increase, zimetidin-lowering metabolism. Do the alcohol, barbiturates and other funds oppressive central nervous system. Disulfiram can provoke deliri, holinolitiki or neiroleptiki - giperpirekshiyu (especially in hot weather).

Overdosing

Symptoms : nausea (possible only after 3-5 days), the expansion of the Micro ECG.

Precautions

Incompatible with MAO inhibitors (a possible no earlier than 14 days after the repeal). Be wary appoint the disease, including stroke, arrhythmia, heart failure. During treatment should be deleted alcohol consumption.

Dosing and Administration

Inside, 25 to 50 mg per night, and then increase the dose over a period of five to six days prior to the 150 to 200 mg / day (most of the dose at night), if necessary, up to 300 mg / sut. With the disappearance of the symptoms of depression reduces the dose to 100 mg / day, and continue to treat at least 3 months. In old age, with light violations is 50-100 mg / day for the night. In enuresis in children under 6 years, 10 mg at night, from 6 to 10 years, 10 to 20 mg / day of 11-do 16-50 mg / day for a period of not more than 6 months.

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