Eprobemide

Chemical name

4-Хлор-N-(3-морфолинилпр опил)бензамид (as hydrochloride)

Gross

C14-H19-Cl-N2-O2

Characteristics

White or white with kremovatam white crystalline powder. Easily soluble in water, soluble in ethanol, little soluble in chloroform, almost nerastvorim broadcast.

Of drugs

Drugs, the antidepressant. Selective and reversible MAO ingibiruet Type A increases monoaminov content in the CNS. Provides antirezerpinovoje act potenziruet fenamina effect. And antidepressivei properties with the stimulant effect. Improves mood, improves psihomotornuyu activity.

Indications

Depression different etiology (if маниакально-депресси��ном psychosis, various forms of schizophrenia, dementia senilna, inwalutinom psychosis, rocket-propelled, neurotic, shallow depression with neurozopodobna and nerezko expressed ipohondricescoy symptoms, etc.). Alcoholism : �стено-субдепрессивны й syndrome, adinamical subdeprescia (deteriorating mood, depression, apathy, increased fatigue), in the absence of anxiety disforicakih violations insomnia.

Contraindications

Hypersensitivity, acute inflammatory diseases of the kidneys, liver, poison control, drugs and analgezirutmi means; Acute alcohol cravings.

Side-Effects

Headache, a sense of gravity in the head, demotion AD (dozozawisimae effects), increased anxiety and irritability, allergic reactions.

Specific guidance

Before the introduction of 0.25% solution raise izotoniceski solution of sodium chloride or 5% glucose solution.

Patient interaction

Compatible with neiroleptikami and tranquillizers.

Precautions

If in the depression and crazy galloucinathornah disorders, anxiety and irritability that combined with tranquillizers and neiroleptikami.

Dosing and Administration

Adults : inwards in / in (or drip struino), in / M.vnutri (after delivery), 30-50 mg, if necessary, to 150 mg, twice a day (morning, and in no case later than 18 hours to avoid the disruption of sleep), daily intake to 400 Mg.pri Psychotic deployed, protracted and resistant depression treatment start with the / in the drip (40-80 drops / min) or / with the introduction of jet (within 1-2 minutes) in the dose of 50 mg, then rising to 150-250 mg. B / drip in a can continue for 20 to 25 days (depending on the dynamics of a depressive disorder) before proceeding to the on / m imposition or oral. In / in a jet spend up to 20 times. B / m : single dose of 10-15 mg, daily, 50 mg.

Directory → Neurotropic funds → 24.2.1 → Eprobemide