Fluacizine

Chemical name

10-[3-(Диэтиламино)-1-окс��пропил]-2-(трифтормети л)-фенотиазина (and as hydrochloride)

Gross

C20-H21-F3-N2-O-S

Characteristics

White or white with weak kremovatam white crystalline powder and odourless, it is difficult soluble in water, easily in alcohol. The dark world.

Of drugs

Drugs, the antidepressant. And central and peripheral m-holinoliticaskoy activity. Antidepressive Effects combined with sedative effect.

Indications

Depressive of different genesis (inwaluie, rocket-propelled and маниакально-депресси��ном psychosis, and schizophrenia treatment neiroleptikami, ticlotimia), including : accompanied by fear, anxiety, stress; as a proof-reader extrapiramidale disorders resulting from the application of doses.

Contraindications

Zakratougolnaya glaucoma, a disease hospital of stomach and duodenal ulcers, liver and / or kidney failure, liver disease (viral hepatitis, cirrhosis), prostate adenoma cancer, atony bladder, poisoning CNS stimulants and antidepressants.

Side-Effects

Reducing AD paresis ccomodation, weakness, nausea, dry mouth, constipation, pain in the limbs, difficulty urinating (requires the preparation).

Patient interaction

Compatible with tricyclic antidepressants, antipsychotic drug, amphetamine. Incompatible with MAO inhibitors. Enhance and prolong fenamina effect.

Precautions

It should not be applied sooner than 1-2 weeks after the lifting of MAO inhibitors.

Dosing and Administration

Inside, the food. Initial dose of 50-70 mg / day in the reception 2-3, and then dose gradually increased. The average therapeutic dose of 200 mg (300 mg) in Sutki.v / m to 25 mg (2 ml of 1.25% solution) 1-2 times a day, and then smoothly dose increase. Higher daily doses of 75-100 mg. When the therapeutic effect gradually moving towards ingesting. Treatment course 4-6 Ned.ekstrapiramidnye violations-on the inside of 10-60 mg 1-2 times a day or / m 10-40 mg / sut.

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