Fluksonil

Roman name

Fluxonil

The composition and the form of

1 tablet contains fluoksetina hydrochloride 10 mg; in the package of 100 pcs. or blistere 10 pcs. , in a package three blister.1 capsule 20 mg; in the package of 100 pcs. or blistere 10 pcs. , in box 3 blisters.

Pharmacokinetics

If ingestion is rapidly absorbed, material-60%; T_1/2 drug - 2-3 days, and its principal metabolita, 7-9 days; Metabolised in the liver, kidneys displayed.

Farmakodinamika

Depression takes different genesis, weakly affects holinergicakie, adrenergicakie and gistaminove receptors.

Clinical pharmacology

The effect develops in 3-4 weeks of admission.

Indications

Depression different etiology.

Contraindications

Hypersensitivity, sudorozhny syndrome expressed by the human kidney simultaneous MAO inhibitors, pregnancy, child.

Side-Effects

Side Effects are extremely rare and occur at doses greater than 20 mg / sut. Headache, dizziness, nervousness, fatigue, insomnia, drowsiness, anxiety, tremor, weakness, dry mouth, loss of appetite, neuralgia, nausea, vomiting, diarrhea, increased sweating, the weakening of sexual desire, anorgazmia, giponatriemia, allergic reactions (skin rashes, savorotocnaya disease thrombocytopenia, trombozitopenica purpura).

Patient interaction

Impact on CNS added hypnotics, anti preparations neiroleptiki analgesics (including drugs), to narcosis, ethanol. When taken with MAO inhibitors, increase body temperature, muscle rigidity, convulsions, ajitation, human consciousness (before deliria and coma); When used with triptofanom - ajitation, anxiety, gastrointestinal symptoms.

Precautions

Be wary appoint patients with cardiovascular diseases, as well as those engaged in activities requiring greater attention (driving, etc.). At the time of treatment nursing mothers should stop breast-feeding.

Dosing and Administration

Inside, on one occasion, in the morning-20 mg (maximum 80 mg), and then gradually dose (at intervals of one week) increased; Daily dose of more than 20 mg taken two reception. In bulimia-60 mg / day (divided by 3 admission).

Storage conditions

List B. At room temperature

Shelf life

3 years

The registration

009,718 (Ann.2002)

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