Tetrindol

Chemical name

2,3,3a,4,5,6-Гексагидро-8-ци клогексил-1H-пиразино[3 ,2,1-j,k]карбазола hydrochloride

Characteristics

White to yellowish or желтовато-зеленоваты�� white crystalline powder. Virtually nerastvorim water, little soluble in alcohol.

Of drugs

Drugs, the antidepressant, psihostimulirutee. Selectively reversible MAO ingibiruet type A. stops dezaminirovanie serotonin, to a lesser extent, norarenalina; Have little impact on the metabolism tiramina (practically no danger Development sarnogo "syndrome). Activity begins in Dna.bystro 2-3 and almost completely absorbed after administration inwards. Easily passes gistogematicalkie barriers, including GEB; Creates high concentrations in the tissues of the brain.

Indications

Depression different genesis (especially ticlotimicski level) : endogenous, psychogenic (reactive, judo), caused injury to the brain or chronic alcoholism, обсессивно-компульси��ный syndrome. When alcoholism : astenodepressivee state and adinamicakie subdepression either underweight mood, podavlennostew, apathy and increased utomlemostew, in the absence of express anxiety, insomnia, disforicakih violations and outside the period of acute illness.

Contraindications

Acute inflammatory diseases of the kidneys and liver, alcohol cravings, pregnancy and breast-feeding (at the end of treatment), infant age.

Side-Effects

Anxiety, headache, sleep disturbance, dry mouth.

Patient interaction

Is not compatible with other MAO inhibitors and alcohol. Ters deprimirotuyu rezerpina activity increases effects fenamina, L-dofa, 5-oxitriptofana.

Overdosing

There is an appearance by Effectov.lechenie : symptomatic washed stomach reception activated carbon.

Precautions

Avoid activities requiring increased physical and mental reactions (of potentially dangerous and complex transport mechanisms).

Dosing and Administration

Inside. Since doses of 25-50 mg per reception, two times a day (morning and afternoon), with a gradual increase to 400 mg / day for 1-2 weeks.

Directory → Neurotropic funds → 24.2.1 → Tetrindol