Glutamic acid

Chemical name

L-glutaminova acid

Gross

C5-H9-N-O4

Characteristics

The white crystalline powder acid taste. It is soluble in cold water, soluble in hot water (pH aqueous 3,4-3,6), almost nerastvorim in alcohol.

Of drugs

The drugs-neiromediatornoe, stimulating metabolism in the central nervous system. Zamenimaya acid, is derived from food, as well as synthesized in the body when pereaminirovanii in katabolizma proteins. Participates in belkovom and uglevonom exchange stimulates oxidation processes from lower окислительно-восстан��вительного potential increases vulnerability to hypoxia. Normalizes metabolism by altering the functional state of the nervous and endocrine Sistem.avletsa neiromediatorna acid, stimulates the initiation of neurotransmission in the central nervous system. Participates in the synthesis of other amino acids, acetylcholine, ATP contributes to the transfer of potassium ions, improves the skeletal muscles (is a component miofibrill). Provides desintoksikatine act to remove and drain from the body of ammonia. Normalizes glikoliza processes in the tissues has gepatoprotectornoe act stupid secretornuu function Jeludka.pri ingestion well absorbed, permeates through GEB and cell membranes. Figure in the process of metabolism, 4-7% appears in the news kept Vide.pokazana the dual use with pahicarpinom or glitzinom with progressive myo.

Indications

Epilepsy (mostly small seizures with equivalents), schizophrenia, psychosis (somatogenne, intokshikaie, inwaluie), the rocket-propelled running events exhaustion, depression, the effects of meningitis and encephalitis, neiropatia chemicals in the face of hydrazides izonicotinova acid (combined with tiaminom and piridokshinom), hepatic coma. In pediatrics, mental retardation, cerebral palsy, the effects of hypoxia intracranial trauma syndrome disease, poliomyelitis (acute and recovery periods).

Restrictions on the use of

Diseases of the kidneys and liver.

Contraindications

Hypersensitivity, fever, liver and / or kidney failure, principally syndrome, a disease hospital of stomach and duodenal ulcers, diseases of the blood, anaemia, lakopenia, anxiety trendy either psychotic reaction obesity.

Side-Effects

Increased anxiety, insomnia, pain in the abdomen, nausea, vomiting, diarrhea, allergic reactions, vomiting, short hyperthermia; In the long-term use, anaemia, lakopenia, mucosal irritation of the oral cavity, cracks in the lips.

Specific guidance

Once inside as a powder or suspension recommended rinsing of the mouth mild sodium Gidrocarbonata.pri development phenomena dispepsii take during or after delivery.

Precautions

During treatment there should be regular publeklinicakih blood and urine. If you have side effects, discontinue use of and see a doctor.

Dosing and Administration

Inside for 15-30 minutes before the meal. Adults and children 10 years or older on 1 g 2-3 times a day. Children : up to 1 year, 0.1 g 1-3 years in the 0.15g, 3-4 years - 0.25 g 5-6 years in the 0.4 g, 7-9 years in the 0.5-1 g, 2-3 times a day; In the mental 0.1-0.2 g / kg The course of treatment for 1-2 and 6-12 months.

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