Tetracaine

Chemical name

4-(Бутиламино)бензойно й acid 2 -(диметиламино)этилов��й broadcast (and as hydrochloride)

Gross

C15-H24-N2-O2

Characteristics

The white crystalline powder, odourless. It is soluble in water, alcohol, physiological solution and the solution dekstrozy.

Of drugs

The drugs - местноанестезирующее . Lock sensitive nerve roots and conductors; Permeates through the membrane of nerve cells, violates transmembranny transport ions (especially sodium), reduces the flow of impulses in the central nervous system; Expands Sossouda.legko absorbed through mucous membranes. Anaesthesia develops over 3-5 minutes and lasts for 30 to 90 minutes. Fully hydrolyses within 1-2 h holinesterzoy education and PABK dietilaminoetanola.

Indications

Local (superficially spinnomozgova) anaesthesia.

Pregnancy and lactation

It may, in exceptional cases, if the effect of therapy outweighs the potential risk to the fetus and newborn.

Contraindications

Гиперчувствительност ь (including from other local groups anestetikam esters or PABK and its derivatives), severe somatic disease, age child (up to 10 years).

Side-Effects

The local application : allergic contact dermatitis, stinging sensation, swelling and pain in the area of application; In the long-term use-keratit resilient plastic cornea, education scars the cornea loss of vision, slowing Epitelizace.pri inject introduction : initiation CNS, depression, nervousness, dizziness, impaired vision, drowsiness, tremor, convulsions, loss of consciousness, heart failure, AD change (usually gipotenzia), cardiac arrest, respiratory disorders, nausea, vomiting, chills, narrowing pupils, noise in the ears, idyoshinkrazia or reducing tolerance, urticaria, anaphylactic shock.

Specific guidance

Tools and syringes, contact with tetrahammo shall not contain residual alkali (unreduced form ground).

Patient interaction

Impact antibakterialnuyu activity sulfanilamidnykh drugs. Sossoudossoujiwate funds lengthened effect and reduces toxicity.

Overdosing

Symptoms : dizziness, general weakness, zianoz, initiation, anxiety, muscle tremor, convulsions, breathing problems, collapse, infants, nausea, vomiting, coma, AV Blokada.lechenie : removal of the skin and mucous membranes washed stomach (via probe), with activated carbon, the appointment of salt laxatives; Oppression in the air, and the IVL rooms, collapse in / with the introduction of products (salt solutions gemodes, poligliukin), the application vazokonstrictorov (preferably enabling miocard), convulsions, diaz f6b2 epam or barbiturates short (in / in), natal 1-2 mg / kg metilenovogo blue (in /) or 100-200 mg ascorbic acid inside.

Precautions

Do not be applied to large areas of damaged skin (the risk of aspiration and systemic toxicity). The nose is not recommended long-term, or even (possibly damaged cornea). To use caution in patients with reduced levels of cholinesterase in the blood plasma, human heartbeat rhythm, AV closures shock. The spinal anaesthesia requires monitoring AD.

Dosing and Administration

For surface anaesthesia - 0,05-1% (with the 2-3%) solution; For children older than 10 years and not more than 1-2 ml 0.5-1% solution in adults to 3 ml of 1% solution. Higher dose for adults 3 ml 3% Rastvora.dl periduralna anaesthesia, 5 ml 0.3% solution 3-4 times at intervals of 5 minutes.

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