Ultrakain va forte

Roman name

Ultracain DS forte

The composition and the form of

1 ml solution for injection contains artikaina hydrochloride 40 mg and adrenalin hydrochloride 6 or 12 mg (ultrakain D-S forte), as well as metabisulfita sodium 0.5 mg; in carpulah to 1.7 ml, in a package of 100 pcs. or sealed to 2 ml, in a package 10 pcs.

Of drugs

Местноанестезирующее . Does depoliarizatia membrane disorder and the perception prevents irritation and nervous system.

Pharmacokinetics

For high diffusion capacity to podslizistom introduction of the oral cavity. Linking protein is 95%. T_1/2 - 25.3 min. The minimal cross the placental barrier, barely out of breast milk.

Clinical pharmacology

The fast begins-after 1-3 min. The pain is not less than 45 minutes (Ultrakain D-S), and not less than 75 min (Ultrakain D-S forte). Healing proceeding smoothly because of the good tissue tolerance and the minimum sossoudossoujiwatm action. Because of the low miss the preparation of its effect on the cardiovascular system a little (very little of the AD and increase HR). It has low toxicity.

Indications

Infiltrazionnaya and provodnikova anesthetic in dentistry in the following ways : neoslojnennoe removal of one or more teeth, preparirovanie decayed cavities and teeth under the crown (Ultrakain D-S); Operations on the nose shells or bones, requiring more expressed Cerebral effect, the operations of the tooth pulp (amputation and pulp extirpation), the removal of the broken tooth (osteotomia) Remove tooth affected apicalnam periodontitis operation Koldwella-Luc, crescozhny osteosynthes, kistectomia, mukyingivale operation resection top of the tooth root, preparirovanie decayed cavities and teeth under crown in patients with a heightened sensitivity teeth (Ultrakain D-S forte).

Pregnancy and lactation

Acceptable. During pregnancy, preference should be given to Ultrakaino D-S.

Contraindications

Hypersensitivity, paroxizmalnaya tachycardia, etc. tahiaritmii, zakratougolnaya glaucoma, bronchial asthma (in patients with a heightened sensitivity to sulfitu).

Side-Effects

Violation of consciousness (until losses), stops breathing, muscle tremor, convulsions, nausea, vomiting, drop or increase AD tachycardia or aetiology, incredible; Produced in the eyes, blindness tricky, diplopia; Headaches, allergic reactions (reddening of skin, itching, conjunctivitis, rhinitis, angioneuroticeski swelling varying degrees of symptoms, including swelling of the upper and / or lower lips and / or cheeks, voice filled with obstruction of glotania, hives, difficulty in breathing); All these phenomena can progress to the development anaphylacticski shock; local reaction, swelling or inflammation at the injection, in some cases, random vnutrisosudistaya injection can result in the development of ischaemic zones in the ground, sometimes progressing to woven necrosis. Side-effects caused by the action of adrenaline (tachycardia, Already, the AD), are extremely rare low 1:200000 (0.5 ml diet) and 1:100000 (1 Coca ml) concentrations of adrenaline. Nerve damage (up to development paralysis of the facial nerve) arise only if there is a violation of injection equipment.

Specific guidance

It individually decide on the admission of the patient to the vehicle, or work with the arrangements.

Patient interaction

Hypertensive effect via enhanced tricyclic antidepressants and MAO inhibitors. Increased risk of gipertoniceski kriza and expressed bradikardii against selective бета-адреноблокаторо��.

Overdosing

At the outset of the development side, or toxicity (dizziness, dwigatelnoe anxiety, impaired consciousness) to the patient and put the patient in a horizontal position; A careful monitoring of hemodynamics (pulse / AD), and road respiratory tract. Even if the symptoms do not seem to be difficult to prepare everything for in / Infusion in, and at least a venepunktia. Depending on the degree of breathing should be oxygen, the artificial respiration (mouth to the nose), and, if necessary, endotrahealnuu intubatia with controlled ventilation lungs. The analepticakih drugs of the central counter. The involuntary muscle podergivaniah or Generalized convulsions shown in / with a short barbiturates or ultrakorotki actions (under the control of hemodynamics and respiration, oxygen input and the simultaneous in / in infuziei liquid). In heavy human circulatory shock and injection drug should be discontinued, the patient horizontal position with pripodnatami legs hold ingalatia oxygen and / in infuziu balanced elektrolitnykh and plazmozameshchath solutions in / in a glukokortikoida (250-1000 mg metilprednizolona). In the case of threatening vascular collapse and growing bradikardii introduce / in the 100 µ g epinephrine (0,25-1 ml concentration of 100 µ g / ml; Slowly, under the control panel and AD); There should be more than 100 µ g epinephrine (1 ml) for the one time. Heavy forms tahiaritmii and tachycardia can be resolved complications of drugs (but not selective бета-адреноблокаторо��). When the AD in patients with arterial hypertension, it is appropriate to apply peripheral vazodilatatora.

Precautions

The issue / in, in ingezirovti area inflammation. In patients with a deficit cholinesterase should be used only for urgent reasons. In Cardiovascular diseases (chronic heart failure, coronary disease receptacles stenocardia, the rhythm, heart attack in history, HBP), cerebrovascular disorders with the paralysis of the disease, chronic bronchitis, emphysema, diabetes, gipertireoze expressed concern to the use of drugs containing fewer sports. There should be combined with neselektivei бета-адреноблокатора��и.

Dosing and Administration

Dose of the drug out individually, taking into account the gravity and duration of early intervention. When you neoslojnennom teeth upper jaw (no skin) have infiltration anaesthesia Ultrahammo dose of 1.7 ml (each tooth); In some cases, it may be necessary to introduce additional 1 to 1.7 ml preparation for the total anaesthesia. In most cases, there is no need to nebnam hour access; Anaesthesia for the nebnykh mines and of the joints to create uvula depot to be about 0.1 ml anestetika to puncture. When you delete a number of the teeth of injection is usually limited. If you delete Danbury lower jaw (in the absence of inflammation) may be dispensed with mandibularna anaesthesia (infiltrazionnaya anaesthesia provided by injection of 1.7 ml per tooth, as a rule, is sufficient; If required, it may introduce additional 1-1.7 ml anestetika, in the absence of effects-blockade nijnecheljustny nerve). To prepare cavities or preparirovania crown under any teeth (except for the lower molarov) on a dose of 0.5 to 1.7 mL for each tooth type branches anaesthesia with vestibular side. Using any medical procedure adults can enter up to 7 mg / kg body weight. Doses up to 500 mg (12.5 ml injection solution) well tolerated in the injection aspiratini samples with a view to avoid the imposition of vnutrisosudistogo (for the most suitable pump "Becton K to karpul).

Storage conditions

r-r d / in. : List B. In the dark place at a temperature of no higher than 25 ° C

Shelf life

r-r d / in. : 2.5 gu.r-r d / in. : 3 and

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