Propofol 1% frezenius

Roman name

Propofol # 1% Fresenius

The composition and the form of

1 ml of emulsion in / in the propofola contains 10 mg; 182,000,000 in 20 ml, in a cardboard bundle five ampoules or vials 50, or 100 ml, in a cardboard bundle 10 or one bottle respectively.

Of drugs

Publeanestezirutee. Decreases cerebral blood and metabolism, intracranial pressure.

Farmakodinamika

It is fast (about 30) offensive pharmacological sleep.

Indications

General anaesthesia (initial and sustaining anaesthesia); The sedative effect in the intensive therapy, IVL, surgical and diagnostic procedures.

Pregnancy and lactation

It should refrain from the use of the drug during pregnancy and lactation (safety for infants is not clear).

Contraindications

Гиперчувствительност ь.

Side-Effects

During induction narcosis : arterial gipotenzia temporary Apdimi.v induction period narcosis : pain in the introduction epileptiformnye Movement (saved in the period of narcosis and awakening), including convulsions, opistotonus rarely-clinical features arginine (angioneuroticeski swelling, bronhospazm, erythema, gipotenzia), thrombosis, Flebit.v period awakening : nausea, vomiting, headache Bol.posle long Use : bleached Mochi.prochie : healthy lungs, postoperative fever, sexual release.

Patient interaction

Not to be confused with any intravenous solutions, but the solution dekstrozy 5% lidocaine hydrochloride for injection, alfentanil for Ingyektion.pri a miorelaksantov atrakuriya bezilata and mivakuriya chloride should not use the same system for the on / in the as for the preparation, without its prior periods.

Overdosing

Symptoms : oppression heart and Dahania.lechenie : should that patient head; If necessary, the introduction plazmozamenitelei and vazopressornah funds. The IVL and kislorodoterapii.

Precautions

Is not recommended in childhood induction narcosis (children under 3 years) and sedative effect. Children over 8 years for induction narcosis An dose of 2.5 mg / kg, less than 8 years, we can even higher dose. Be wary used for narcosis in patients with epilepsy (can develop lung), cardiovascular disease, kidney, liver, the breathing apparatus gipovolemiei severely weakened. In maintaining anesthesia through continuous or bolusni introduction in patients with lipid exchange need to be monitored lipids in the blood, and when they increase, reduce dose.

Dosing and Administration

In / in bolusno or infuzionno, titration method (before clinical signs of pain). Before applying ampoules or bad should Ustrahnuti.vesroslam : with the introductory lecture, in the dose of 1.5-2.5 mg / kg to 40 mg every 10 to (patients over the age of 55 requires a smaller dose and the rate of 20 mg every 10 sec); For the maintenance of anesthesia, 4-12 mg / kg / hour (constant in / in cefuroxim) 25-50 mg (re bolusnye introduction); for the sedative effect at the time of intensive care-infuzionno Quick 0,3-4,0 mg / kg / h; for the sedative effect in patients who are in the minds, during surgical and diagnostic procedures, 0.5-1.0 mg / kg within 1-5 minutes (for the effect Quick infusions of 1.5-4.5 mg / kg / h). Children over three years : for the maintenance of anaesthesia-Quick Infusion 9-15 mg / kg / h or re bolusno.

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