Alimemazine

Chemical name

N,N,бета-Триметил-10Н-фе��отиазин-10-пропанамин (and in the form of tartrate)

Gross

C18-H22-N2-S

Characteristics

Derived fenotiazina. White or slightly yellow crystalline powder, soluble in water and alcohol.

Of drugs

Drugs, the neuroleptic, sedative, antigistaminnoe, protivorvotnoe. Quickly and completely absorbed in any of the introduction. The plasma 20-30% is associated with malnutrition. T_1/2 - 3.5-4 hours The liver oxidized to sulfoxida. Write mainly via the urine (in 2 days excreted about 70-80%). The effect is 15 to 20 minutes after the introduction and lasts 6-8 hours

Indications

Neuroses and neurozopodobne of endogenous and organic genesis-dominated senestopaticakih, ipohondricakih, fobicakih and psichowegetativeh disorders; Psychopathy with asthenia or психоастеническими disorders; тревожно-депрессивны�� of the border and endogenous vascular diseases; senestopaticalkie depression somatizirovanne mental disorders; of the unrest and unease somatic diseases; sleep disturbance different genesis, allergic reactions.

Contraindications

Hypersensitivity, zakratougolnaya glaucoma, diseases of prostate cancer, severe liver damage and kidney failure, pregnancy, breast-feeding (at the end of treatment), up to one year.

Side-Effects

Drowsiness, weakness, dry mouth, increased viscosity Bronchus secret paresis ccomodation, constipation, delayed urination, ekstrapiramidnye disorders (hypokinesia, tremor).

Patient interaction

Increases effect pills, narcotic analgesics, alcohol and for narcosis. Antiholinergicakie substances added atropinopodobnuu activity.

Precautions

It is not to drink alcohol at the time of treatment. Older patients to be reduced dosing. The / m injections are only in the rest. It should be noted that the injection contains sulphites, which can increase the reaction anaphylacticski Tipa.s caution designate drivers transport and those working with potentially dangerous machinery.

Dosing and Administration

Inside, in / m, / 386/1989 Daily dose is 3-4 at the reception. Designate inside of 10 mg (as a Red) to 80 mg (as anksiolitik) in the night with Psychotic conditions to 200-400 mg in Sutki.v / in the drip-25 mg (starting dose) with a further gradual increases to 75-100 mg.

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