Benperidol

Chemical name

1-[1-[4-(4-Фторфенил)-4-окс��бутил]-4-пиперидинил]-1 ,3-дигидро-2Н-бензимида зол- 2-on

Gross

C22-H24-F-N3-O2

Characteristics

White or white with a slightly kremovatam white crystalline powder. Virtually nerastvorim water, little soluble in alcohol.

Of drugs

Drugs, the neuroleptic, antipsihoticescoe, protivorvotnoe, gipotermicescoe. Does D_2-dofaminove receptors, and the limbic system mezokorticalna (antipsihoticeski effect), a trigger point vomitoxin (protivorvotnoe effect), adrenoretseptora retikuliarna formations barrel brain (neirolepticeski, sedative effect), dofaminove receptors hypothalamus (gipotermicescoe effect). Provides antiserotoninovoe effect.

Indications

206 initiation of different genesis, psychosis (acute, podostry, aged); Maniakale, and maniakalno-bredove галлюцинаторно-бредо��ые disorders, including with schizophrenia and маниакально-депресси��ном psychosis.

Restrictions on the use of

Arterial gipotenzia, feohromotsytoma, liver and / or kidney failure, bronchial asthma, glaucoma zakratougolnaya, prostate adenoma cancer, depression, pregnancy and breast-feeding.

Contraindications

Hypersensitivity diseases of the central nervous system pyramid and ekstrapiramidna symptoms.

Side-Effects

From the nervous system and sensory organs : ekstrapiramidnye disorders (hypertension muscle, tremor, suffering visibility, dizartria, wryneck, akatizia), autonomic lability, dizziness, headache, drowsiness, depression, anxiety, Trevoga.prochie : dry mouth, sweating, loss AD aetiology, the acute urine retention.

Patient interaction

Do the pills means, of narcosis and narcotic analgesics.

Precautions

It should not be used in conjunction with the drivers of vehicles and people skills relate to the high concentration of attention.

Dosing and Administration

V / m, the initial dose of 1-2.5 mg / day in a 2-3, followed by the increase in the 4-7 days prior to the therapeutic effect (usually 4-7,5 mg / day). The maximum daily dose is 15 mg. The course of treatment to two months or more.

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