Fluspirilene

Chemical name

8-[4,4-бис-(4-Фторфенил)бу тил]-1-фенил-1,3,8-триаза��пиро[4.5]декан-4-он

Characteristics

Mikrochristalliceski powder insoluble in water.

Of drugs

Drugs, the neuroleptic, antipsihoticescoe. Facilitates adaptation and rehabilitation patients. After a single on / m of C_max achieved through 6700, T_1/2 about 3 weeks, the duration of 15 days.

Indications

Psychotic disorder with a productive and negative symptoms : hallucinations, delirium, autism, emotional and agitation et al; Maintenance therapy of chronic mental illness after treatment in hospital.

Contraindications

Hypersensitivity, ekstrapiramidnye violations, depression, I trimester of pregnancy.

Side-Effects

Nausea, a sense of fatigue, ekstrapiramidnye disorders, reducing body weight, weakness, deterioration of sleep, depression.

Precautions

To prevent extrapiramidale disorders recommended in a day and the subsequent two days to appoint противопаркинсоничес кие funds.

Dosing and Administration

V / m. The patient : once a week, first by 4-6 mg (2-3 ml suspension), as necessary, before 8-10 mg (5 ml). After optimal dose effect gradually reduced to a supporting-2-6 mg (1 ml) weekly. Leaving the treatment every 3-4 weeks a long break. The outpatient impose on 2-6 mg once a week.

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