Galoperidol-akri

Roman name

Haloperidol-Akri

The composition and the form of

Pill-1 tabl.galoperidol 1.5 or 5 megawatts contour acheikova packing 10 pcs. ; In the paper cartons 5 or 10 (5 mg) packages.

Pharmacokinetics

The ingestion absorbed by 60% C_max achieved through 3-6 hours The allocation is 18 l / kg The blood 92% is associated with malnutrition. Treated biotransformation in the liver. T_1/2-24 hrs (p 12-37). 40% of a single dose of return with urine for a period of five days (1% in unmodified form), and 15% from faeces. Cl-12 ml / kg / min.

Farmakodinamika

It stimulates the metabolism brain has trankvilizirutee and expressed protivorvotnoe effect; Ekstrapiramidnye of propulsion reaction; Reduces release somatotroponogo and hormone-enhanced prolactin. Changes concentration of dopamine.

Indications

Acute and chronic psychotic disorders (schizophrenia, psychosis) syndrome goes De La Turetta, child autism, trochaic Gentington, uncontrollable vomiting, prevention and treatment of nausea and vomiting in chemotherapy.

Pregnancy and lactation

Contraindicated. At the time of treatment should stop breastfeeding.

Contraindications

Hypersensitivity diseases of the central nervous system pyramid and ekstrapiramidna symptoms, the heavy oppression of toxic substances caused by drugs, depression, hysteria, pregnancy, breast-feeding, child age (up to 3 years).

Side-Effects

Akatizia, ekstrapiramidnye disorders persistirutaya diskinesia late, late distonia, antiholinergicakie effects, reducing fluid intake, fatigue or weakness, ortostatical gipotenzia, agranulozitos, obturazionnaya jaundice, neirolepticeski malignant syndrome, the symptoms nesharnogo diabetes, glaucoma increase, the trend towards monocitoza, allergic reactions.

Patient interaction

Do antigipertenziveh effects of opioid analgesics, barbiturates, ethanol and etanolsoderjath drugs. When coupled with the admission epinefrinom possible arterial gipotenzia and tachycardia.

Precautions

Be wary appointed in cardiovascular disease events decompensation, violations conductivity attack, heavy kidney diseases. In the case of psoriasis later, there is a need to reduce the dosage and use the other product. It should not be used in conjunction with the drivers of vehicles and people skills relate to the high concentration of attention. During the prohibited use of alcohol.

Storage conditions

List B. In a dry, the dark place at a temperature of no higher than 25 ° C

Shelf life

3 years

The registration

002707/01-2003

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