Klopicksol depot

Roman name

Clopixol Depot

The composition and the form of

1 ml solution for injection contains zuklopentixola dekanoata (vegetable oil Viscoleo ®) 200 mg; in the package 10 vials 1 mle.1 ml solution for injection 500 mg; in the package one or five vials of 1 ml.

Indications

Acute and chronic schizophrenia and other psychotic disorders, especially hallucination, paranoid illusion, human thinking; Ajitation condition, high anxiety, hostility, aggressiveness (maintenance therapy).

Pregnancy and lactation

Contraindicated. Nursing mothers should stop breast-feeding.

Contraindications

Acute alcohol poisoning, barbituratami, opiates; Komatosnye state.

Side-Effects

There ekstrapiramidnye violations late diskinesia, neirolepticeski malignant syndrome, drowsiness, dizziness, dry mouth, a breach of ccomodation whose urination, constipation, tachycardia, ortostatical gipotenzia, changes in liver samples.

Patient interaction

Do effects of alcohol, barbiturates and other funds oppressive central nervous system, reduces levodopa, etc. adrenergicakih substances. Ters gipotenzivne influence guanetidina and its analogues. The risk of disorders extrapiramidale increase metoclopramide and piperazine. Can interact with Klopicksolom-akufaz (ko-ingyekcia).

Precautions

With the utmost care to appoint sudorozhnom syndrome, chronic hepatitis, cardiovascular diseases; Persons administering car, etc. mechanisms. With long-term therapy, especially in high doses, a careful monitoring of the patient.

Dosing and Administration

V / m, in the upper outer quadrant rump end. Dosage and the interval between injections are individually, in accordance with the state of the patient. Klopicksol depot 200 mg / ml : for maintenance therapy appoint usually 200-400 mg (1 ml) every 2-4 weeks; If necessary, in higher doses, or at shorter intervals; With the solution (200 mg / ml) is 2-3 ml is preferable to use a solution greater concentration (500 mg / ml). Klopicksol depot 500 mg / ml : usually impose on the 250-750 mg (0.5-1.5 mL) every 1-4 weeks. The transition from oral to Klopicksola Klopicksol depot daily oral dose (in mg) multiplied by eight. The / m impose dose once every two weeks; During the first week there is a need to continue oral, but in a reduced dosage. At the transition from Klopicksola-akufaz at the same time as the last injection drug appoint 200-400 mg (1 ml) Klopicksola depot, repeated injections, every 2 weeks; If necessary, increase the dose or shorten the interval between wvedeniami.

Storage conditions

List B. In the dark place at a temperature below 25 ° C

Shelf life

3 years

The registration

014165/01-2002

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