Mirenil

Roman name

Mirenil #

The composition and the form of

1 tablet contains flufenazina dihydrochloride 0.25, or 1 mg; in the package 30 or 60 pc. respectively.

Of drugs

Antipsihoticescoe. Does dofaminove D_2-retseptora in the CNS. Provides inhibitive effect on the formation retikuljarnuu barrel brain reduces its aguirutuyu impulsaciu in the cortex.

Pharmacokinetics

Well drawn. Passes gistogematicalkie barriers, including GEB and placental, presented with urine and partly from jelchew.

Clinical pharmacology

It has a strong and long antipsihoticescoe effect. The neurotic activity 25 times stronger aminazina. Sedatives and neuro properties weaker than other derivatives fenotiazina. In low doses stimulates motoriku.

Indications

Acute and chronic psychosis, either with the phenomena of fear, anxiety and mental institution; Psychosis shizofreniceski type, especially with a picture of apathy and indifference; Senile psychosis.

Contraindications

Hypersensitivity, organic diseases and injuries brain (especially hypothalamus), acute depressive condition, epilepsy, feohromotsytoma, lakopenia, kidney, liver and heart failure, coma.

Side-Effects

Fall, block, violations of coordination, disorientation, depression, parkinsonism, a decline AD of the conductance and heart rhythm, ECG changes, nausea, vomiting, constipation, holetsatical jaundice, disease, rhinitis, agranulozitos, hyperpigmentation skin, dermatitis, galactorea, amenorea, ginekomastia men, the increase in body mass index, photosensitization, kozhnoallergicakie manifestations.

Patient interaction

Do psychological effects, etc. of oppressive central nervous system.

Precautions

If long-term use is required in the control cells and the functional liver samples. Be wary appointed to insufficient mitral valve, the risk of heart problems, combined with hypotensive means.

Dosing and Administration

Inside, determine dose, depending on the patient and his sensitivity to the drug. Treatment start with small doses, gradually increasing them to achieve an optimal effect. Adults : 1-5 mg / day, if necessary (in the hospital), 10 mg / sut. Daily dose taken 3-4 reception. Older patients appoint half dose. The conditions concern tension and fear appoint one dose of 1-3 Mg.detam (only in exceptional cases) : 0.25 mg / sut.

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