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Piportil l4See also PipotiazineRoman namePiportil L4The composition and the form ofUSD 1, or 4 ml of oil for a / m injection contains pipotiazina palmitate 25 or 100 mg respectively; In a carton 3 or 1 USD respectively.Clinical pharmacologyIt has an overall effect on the set of Psychotic processes reduces psihoticescuu symptoms, reducyruet psihoticeski fear depersonlizatia, agitation, aggressiveness, contradictions, eliminates psihomotornuyu block. The active substance drug slowly released during the hydrolysis of palmitate in the introduction, thereby avoiding the daily injections.IndicationsChronic psychosis, delusional disorder, schizophrenia.Pregnancy and lactationWith caution because of safety has not been established.ContraindicationsA toxic agranulozitos in history, zakratougolnaya glaucoma, porphyria, and prostate disease.Side-EffectsDejection, psoriasis : early (spazmatical wryneck, okulomotornyi kriz, trism), and later, ekstrapiramidnye violations; Ortostatical hypotension, dry mouth, constipation, paresis ccomodation whose urine; Impotence, frigidity, amenorea, galactorea, ginekomastia, giperprolaktinemia, increased body mass index; Hyperthermia, holetsatical jaundice, photosensitization, agranulozitos (very rarely).PrecautionsWhen gipertermii appointment immediately cease. It accurately monitor required for the treatment of epilepsy (with regard to the possible lowering of the threshold epileptogennogo) and parkinsonizma. Caution is needed in the appointment of older patients (sedative and gipotenzivny effects); In cardiovascular disease, kidney or liver failure; Drivers transport and those working with (sleepiness and reduced reaction, particularly at the beginning of treatment).Dosing and AdministrationInjections Piportila L4 appointed after taking Piportila inside. Enter deeply into / m (avoid suicide) first in a hospital, then out-25-200 mg (1 ml) once a month. Older patients and those with epilepsy BSE and alcoholism, the initial dose of 25 mg and increased to the extent necessary. Children, depending on age, the initial dose of 12,5-50 mg, with an increase to 100 mg.Storage conditionsList B. In the dark place at a temperature of no higher than 25 ° CShelf life4The registration00806 (Ann.2002, BRP) |
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