Directory → Neurotropic funds → Neiroleptiki → Piportil
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PiportilSee also PipotiazineRoman namePiportilThe composition and the form of1 tablet contains pipotiazina 10 mg; in blister packing 10 pcs. , in a cardboard box two blister.1 drop 4% solution for the reception inside the 1 mg; Patients in the 10 ml, in a carton one bottle.PharmacokineticsAbsorbed quickly bioavailability is about 40%. C_max blood-in 1-2 h after administration. T_1/2 - 4-5 days. Write largely through the intestine with the bile excretion; 5-10% is allocated through the kidneys.Clinical pharmacologyIt has an overall effect on the set of Psychotic processes reduces psihoticescuu symptoms, reducyruet psihoticeski fear depersonlizatia, agitation, aggressiveness, contradictions, eliminates psihomotornuyu block. A more lasting than other neiroleptiki. And satisfactory tolerance.IndicationsChronic psychosis, or deficitarnaya of paranoid schizophrenia, gebefrenia, chronic galloucintorne and affeguo-bredove state. Acute psychosis and acute crises of chronic illness-maniakale attacks nonsense attacks of various kinds, the institute.Pregnancy and lactationHarmlessness use in pregnant and breastfeeding is not installed.ContraindicationsA toxic agranulozitos in history, zakratougolnaya glaucoma, porphyria, and prostate disease.Side-EffectsDejection, psoriasis : early (spazmatical wryneck, okulomotornyi kriz, trism), and later, ekstrapiramidnye violations; Ortostatical hypotension, dry mouth, constipation, paresis ccomodation whose urine, impotence, frigidity, amenorea, galactorea, ginekomastia, giperprolaktinemia; Increase in mass body hyperthermia, holetsatical jaundice, photosensitization, agranulozitos (very rarely).OverdosingPerhaps an acute syndrome parkinsonizma and coma. Treatment of symptomatic.PrecautionsWhen gipertermii treatment immediately cease. It accurately monitor required for the treatment of epilepsy (with regard to the possible lowering of the threshold epileptogennogo) and parkinsonizma. Caution is needed in the appointment of older patients (and sedative effects gipotenzivny), and heart disease, kidney or liver failure, the transport drivers and those working with (sleepiness and reduced reaction, particularly at the beginning of treatment).Dosing and AdministrationInside, once a day, usually in the morning. Initial dose, 10 mg, the average therapeutic dose-20-30 mg. The dosage may be increased to 60 mg / day, and if possible, to return to the average therapeutic dose.Storage conditionsList B. In the dark place at room temperatureShelf life4The registration012617/01-2001 |
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