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Serokwel

See also Quetiapine

Roman name

Seroquel

Pharmacokinetics

The plasma protein binds to 83%. T_1/2 about 0730 Return with the urine (73%) and faeces (21%) of active metabolites. Biotransformiroetsa with zitohroma P450.

Indications

Acute and chronic psychosis, including schizophrenia.

Pregnancy and lactation

Perhaps if the effect of therapy outweighs the potential risk to the fetus. At the time of treatment should stop breastfeeding.

Contraindications

Гиперчувствительност ь.

Specific guidance

It should not be used in conjunction with the drivers of vehicles and people skills relate to the high concentration of attention.

Patient interaction

Effect weaken induktora mikrosomaionah liver enzymes (phenytoin, carbamazepine, barbiturates, rifampicin) and tioridazin (increases Cl).

Precautions

Caution must be exercised in combination with other drugs, with a central activity with alcohol, as well as in combination with a potential inhibitors biotransformation - ketokonazolom, eritromitinom et al.

Storage conditions

List B. At temperatures below 30 ° C

Shelf life

3 years

The registration

013468/01

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