Uric gamma-hydroxybutirate

Chemical name

4-gidrokshibutanova (gamma-oksimaslana) acid salt calzieva

Characteristics

The white crystalline powder and odourless, easily soluble in water.

Of drugs

Drugs - the properties. Gamma-hydroxybutyric acid is a structural analogue gamma-aminomaslana acid metabolite brain tissue and endogenous neiromediatorom. Increases resistance to cerebral hypoxia and toxic substances, increases the utilization of glucose and oxygen, has nootropona activity and stimulates anabolic processes in the neuron affects dopamine metabolism and serotonin. Normalizes the functional activity of neurons. Provides trankviliziruty effect without causing miorelaxation, prevents the development of neurotic disorders and vegetative reactions in response to the stressful effects. Sedative effect combined with a minor stimulant effect (rising and the antiastenicescoe). And adaptogennami properties and analgeticescoy Aguostew.bystro drawn from the blood, bioavailability of 80%. C_max achieved through 1.5 h after administration. It passes through GEB and placenta. T_1/2 - 1.17 pm

Indications

Neuroticescoe and neurozopodobnoe disorder caused psihogennam effects of toxic or traumatic central nervous system damage; Insomnia; Chronic alcoholism, abstinence syndrome dominated asteno-depressivna and asteno-wegetativoy symptoms.

Pregnancy and lactation

Contraindicated in pregnancy.

Contraindications

Hypersens ffa itivity, pregnancy, infants expressed human liver and kidneys.

Side-Effects

Headache, arousal, shortening time night or sleep disturbances afternoon, nausea, allergic reactions.

Patient interaction

Potenziruet of barbiturates, analgesics (such as morphine) and the psychological means.

Precautions

Because of the sedative effect should not be used during the day to drivers of vehicles and people skills relate to the high concentration of attention. During treatment is not recommended to consume alcohol.

Dosing and Administration

Inside, before delivery, to 0.25 g 3-4 times a day. The maximum single dose tolerance and maximum daily intake to 4.0 g. The course of treatment for 2 to 4 weeks may re courses.

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