Zerebril

Roman name

Cerebryl

The composition and the form of

1 tablet coated liner contains pyracetam 800, or 1200 mg; in a container 30, 60 or 20 and 60 pc. sootvetstvenno.1 syrup ml and 200 mg; in vial 250 ml complete with thick stakanchikom.1 feet from 250 ml for the infusions - 1912

Of drugs

Properties. Activates exchange phosphorous compounds (APF, phospholipids, etc.) in the brain cells of cortex brain.

Pharmacokinetics

The ingestion quickly and almost completely absorbed. C_max achieved in 30 min. Easily permeates through gistogematicalkie barriers, including GEB. Collected in likwore, milk. Within 30 hours (full and unaltered) display memory; T_1/2 blood - 4,5 p, in the brain (likwore) - 7.7 hours

Clinical pharmacology

Is normalization function of the brain, improves memory psihomotornuyu activity facilitates learning, the social rehabilitation of patients eliminates neurological and psychiatric complications, restores the ability to adjust rapidly in the environment, a normal mental activities. Effect develops gradually.

Indications

Cerebral insufficiency as a result of cerebral circulation (including severe), disorders of metabolism head injuries, neurosurgical interventions, stroke, and others, the decline интеллектуально-мнес��ических functions (including memory, the ability to focus, orientation), block, violations emotsyonalno-woleva areas variability mood, dizziness, headache, etc. Psihoorganiceski syndrome (also for senilna dementia, alcoholism, drug addiction), the syndrome of alcohol or cannabis (in / in the introduction).

Pregnancy and lactation

Contraindicated in pregnancy (especially in the first 3 months). Lactoirute women should give up breast-feeding.

Contraindications

Гиперчувствительност ь (incl. to lactose).

Side-Effects

Nervousness, anxiety, insomnia, increased libido, aggressiveness, suetlivosti, agitation (especially with organic dementia), or depression, drowsiness; Nausea, increased slunootdelenie, increased appetite, neuralgia, increased body mass index, dizziness, lability AD; Allergic reactions (including skin rashes), the reduction of the threshold of convulsing (with epilepsy).

Specific guidance

Because of the risk of the state of anxiety and hyperactivity of the zerebrila irreversible severe violations or primary processes atrophy in the brain (senillnaya dementia, Pick's disease, Alzheimer's disease), in most cases, impossible.

Patient interaction

Increases effects of hormones the thyroid gland, and the doses of psychotropic etc., enabling CNS, as well as increased cerebral blood circulation weakens (reduces sudorozhny threshold) protivosudorozhnykh drugs.

Precautions

Be wary appointed to depression accompanied by the state of anxiety, heavy forms of renal failure (recommended strict medical control), in the face of epilepsy. Avoid abrupt withdrawal of treatment.

Dosing and Administration

Inside, in / 386/1989 Answers : during or after eating, squeezed small amounts of liquid; In the dose of 2.4 g / day for 3 admission, as appropriate dose increased to 4.8 g; With the improvement of symptoms to reduce the daily intake - 1,2-1,6 G.sirop : before or during delivery, adults in the usual dose-to 6 ml (1 cup graduated) twice a day (or 4 ml three times a day); if necessary, increase the dose to 6 mL three times a day; with the improvement of symptoms, and 4 ml twice a day; children usually 2 ml three times a Deny.rastvor give / in infuzionno in acute cases, in a daily dose of 12 grams per introduction; if necessary, up to 24 to 48 grams in several varieties. The subsequent move to the reception oral forms. Treatment hold for a long period. If any of the kidneys reduce the dose.

Storage conditions

r-r d / inf. : List B. In the dark place at a temperature of no higher than 25 ° Csirop : List B. The temperature is not above 25 ° Ctabl.p.o. : List B. In the dark place at a temperature of no higher than 25 ° C

Shelf life

r-r d / inf. : 3 g.sirop : 2 g.tabl.p.o. : 5 years

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