Deanol aceglumate

Chemical name

N-azetilglutamat 2-(диметиламино)этанол а (1:1)

Gross

C11-H22-N2-O6

Of drugs

Drugs, the properties, zerebroproteguoe, antiastenicescoe, antidepressant, gepatoproteguoe. It has structural similarity with the GABA and glutaminova acid. Is neirometaboliceski driver has zerebroproteguoe, properties, and psihostimulirutee psihogarmonizirutee effect. Making fixation processes, consolidation, and replication of information improves the ability to Obucheniu.obladaet biodostupnostthew high. Through 0.5-1 h after oral admission detected at the highest concentration in the brain, liver, kidneys, blood plasma, heart. T_1/2-24 p.m. In experiments on animals has expressed antiamnesticescoe act contributes to a memorial trail and hinders its extinction, optimizes learnin 5a8 g. Facilitates transfer of the institution mainly monosinapticski routes improves the rhythm of the EEG and run mejpolusharne differences. There has miorelaksirutm and sedative effect, does not violate the coordination of movements in a wide range of doses (50-1000 mg / kg), is giperstimulatia and Privkanye.obladaet gepatosasitnami properties. The experimental liver problems in animals at doses 25 mg / kg reduced transaminaz level in the serum, improves lipid exchange : lowers triglyceride levels and free cholesterol, raising phospholipids and neeterificirovannah fatty acids. Normalizes gistostrukturu liver, reduces the protein and fat malnut 5a8 rition index to liver (2-5 times) and the extent zirroticeskih Priznakov.pri introduction animals 200 and 2000 mg / kg for 1 month had revealed violations of metabolic functions of the liver and kidneys. When a pregnant rats in the dose of 2000 mg / kg during pregnancy, or two weeks before, there had been tertogennogo and embriotoksicski action. Malotoksicen has no effect allergizirutm not irritating the mucous membranes JKT.V clinical trials show with Pichinde and adinamicakih disorders, including with schizophrenia. Increases activity improves mood, reduces side-effects doses not bad psihoticescuu symptoms. In human intellectual activity and asteno-apaticakih disorders contributes to the overall increase, the interest in the life and communication, improve concentration, reduce intellectual istoshchaemosti. Shown with the biggest problems, violations operator of Pichinde conditions in gerontology, in the age of functional violations (of repentance in the face of insufficient organic brain fatigue, intellectual istoshchaemosti and late endogenous psychosis). In appointing the children had expressed therapeutic effect with Pichinde and asteno-depressiveh conditions in the schizophrenia, istoshchaemosti intellectual and learning difficulties (improves focus facilitates learning and learning). The older children psihostimulirutee by the timolepticski Effectom.effectiven for cupping алкогольно-абстинент��ого syndrome (somato-wegetativogo component and asteniceski syndrome), including : , in conjunction with traditional means (accelerates mild). Improves adapt to overcome long distances to the West or East through climatic zones, in the heat, cold, etc., enhances the Sportsmenov.u patients with acute and chronic liver diseases reduces weakness, drowsiness, skin elasticity, reduces the cium and transaminaz, El cholestasis, normalizes pigmentosa exchange (not violate belkovosinteticescuu liver function).

Indications

Asthenic and asteno-depressivee disorders (border state psihoorganiceski syndrome, schizophrenia, alcoholism), neirolepticeski syndrome (light and medium gravity of), alcohol withdrawal syndrome dominated somatovegetativeh and Pichinde disorder интеллектуально-мнес��ические Violations and neurotic disorders neurozopodobne amidst �езидуально-органичес кой CNS inferiority, psychosomatic Rasstroistva.ostry and chronic hepatitis, cirrhosis, holetaz, muscular dystrophy liver different genesis, incl. alcohol; combination depressive disorders and diseases of the liver.

Contraindications

Гиперчувствительност ь.

Side-Effects

There may be allergic reactions.

Dosing and Administration

Inside, and 1 c.lojke (5 ml containing 1 13a g deanola azeglumata) 2-3 times a day during daylight hours (last admission no later than 18 hours). The maximum single dose of 2 g, the maximum daily intake - 1910 treatment course-half months.

Literature

Nooclerin new domestic nootrop (scientific review) .- M. Ltd. "PIK-FARMA, 2002 - 32.

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