Idebenone

Gross

C19-H30-O5

Of drugs

Drugs - the properties. He has structural similarities to koenzimom Q10. Improves blood circulation and brain delivery for oxygen. Does metabolic processes in the brain : increased synthesis of glucose, APF, to eliminate lactate. Wrinkles peroxide oxidation of lipids and membrane protects neuronal and mitochondrial damage. Modulating neirofiziologicakie reaction brain structures. Shown effective in treatment of hereditary diseases muthondrialnah (Melas-sindrom have atrophied optic nerve Leber, illness Leigh), and mud Friedreiha.dostatern fully absorbed from the digestive tract. Time to C_max - 4h In large quantities permeates through GEB and well distributed in the tissues of the brain. Excreted kidneys. Not koumouliruet.

Indications

Lack of cerebral circulation (Moderate psihoorganiceski syndrome), including : if there is a violation of cerebral circulation, age inwaluih changes in the brain, etc.; zerebrasteniceskie vascular disorders, traumatic, psihogenna etiology; dysfunctions of central nervous system (extinction memory, attention, intellectual productivity, emotional dependence); asteniceski, depression and astenodepressivny syndrome; headache, dizziness, noise in the ears.

Restrictions on the use of

Pregnancy, breast-feeding.

Pregnancy and lactation

Perhaps with caution.

Contraindications

Hypersensitivity, kidney failure.

Side-Effects

Mental institution, the cerebellum, headache, neuralgia, allergic reactions.

Precautions

Be wary of during the drivers of vehicles and people skills relate to the high concentration of attention.

Dosing and Administration

Inside, after eating, to 30 mg three times daily (last admission no later than 17 hours) within 1.5-2 months. If necessary, a 2-3 courses a year.

Literature

1. Muthondriale hereditary disease : methodological approaches to the diagnosis and treatment / / Bulletin of the Moscow medical genetics .- 1996 .- C. 9-17.2. Temin PA, M. Nikanorov, Nikolaeva EA MELAS Syndrome (muthondrialnaya engjefalomiopatia, lactat-atidoz, insultopodobne episodes) : Key events for diagnosis, the лечения//Неврологичес кий Magazine-1998-N 2-C 43-48.

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