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Lucetam

See also Piracetam

Roman name

Lucetam

Pharmacokinetics

Quickly and almost completely absorbed from the digestive tract. Bioavailability 100%. C_max is 30 to 60 minutes. Easily permeates through gistogematicalkie barriers, including GEB. Accumulating in the spinal fluid (C_max determined through 2-8 h), milk. T_1/2 of plasma-4-5 hours of spinal fluid 6-8 hours There is metabolized. Within 24-30 hours almost completely withdrawn (in the unedited version) of memory (90%), is a tract of about 1-2%.

Indications

Atherosclerosis brain zerebro-vasculiarnaya chronic malnutrition, Stroke parkinsonism, post-trauma brain surgery, stroke (westibulopatia, mioclonus crimes origin, speakers, etc.), organic psihosindrom (vascular dementia, Alzheimer's disease, dementia senillnaya alzgeimerovsky type), komatosnye of vascular, traumatic or toxic genesis, and cravings psihoorganiceski syndrome with chronic alcoholism, impaired memory, reduction of concentration in old age, learning of the children (in a combination therapy), sickle cell anemia (in a combination therapy).

Pregnancy and lactation

Contraindicated in pregnancy. At the time of treatment should stop breastfeeding.

Contraindications

Hypersensitivity, severe renal insufficiency (Cl creatinine less than 20 ml / min), ajitirovannaya depression, pregnancy, breast-feeding, child up to 1 year.

Patient interaction

In combination with drugs affecting the central nervous system may increase their effects drugs hormones thyroid-emergence of side-effects of the central nervous system (tremor, anxiety, irritability, sleep disturbances and sputannosti consciousness).

Precautions

Be wary when appoint gipertireoze, epilepsy (correct dose противоэпилептически х funds). There is a need for constant medical monitoring for patients with the human kidney (frequent survey control of the kidney). The geriatric patients before appointment should carefully examine the kidneys. There is a need for caution in a hormone the thyroid gland. Treatment stop gradually. Be wary of during the drivers of vehicles and people skills relate to the high concentration of attention.

Storage conditions

List B. The temperature 15-25 ° C

Shelf life

3 years

The registration

011123

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