Contemnol

Roman name

Contemnol #

The composition and the form of

1 tablet prolonged action of lithium carbonate 500 mg; in glass bottles of 100 pcs. , in the box one bottle.

Of drugs

Antipsihoticescoe, sedative. Does transport of sodium ions in nerve and muscle cells. Ingibiruet inozil-1-fosfatazu and reduces neironalnogo inozita regulating neuronal sensitivity. Increases dezaminirovanie norarenalina and reduces its content in the cell increases serotoninergicescuu activity increases the sensitivity of neuronal brain, including gippocampa to dofaminu.

Pharmacokinetics

It absorbed in the digestive tract. C_max plasma achieved through 9:00 Report the news.

Clinical pharmacology

Preventive extends for six months while maintaining the concentration of lithium in the plasma within 0.6-1 mmol / O Early treatment can trigger depression or maniacal state.

Indications

Prevention maniakalna phase маниакально-депресси��ного psychosis and cyclical aggressiveness of the psihopatov, quarterly binge, some drug addiction, sexual deviations, migraine, Ménière syndrome.

Pregnancy and lactation

Contraindicated.

Contraindications

Heavy disorders of the kidneys and cardiovascular system; Violations vodno-elektrolitnogo balance (simultaneous treatment dioretikami, bessolevaya diet, the lack of sodium, diarrhea, vomiting).

Side-Effects

Brown mouth, diarrhoea phenomenon, tremor, drowsiness, reduced ability Concentrate kidney poliuria, violations of heart rhythm, blood and the functions of the thyroid gland, piodermia, alopecia.

Patient interaction

When combined with neiroleptikami and timoleptikami can increase body weight. Simultaneous use dioretikov leads to giponatriemii. Indometacin, ibuprofen and diclofenak slow excretion of lithium. Противовоспалительны е and laxatives to increase loss of fluids and reduces portability lithium. Incompatible with alcohol.

Overdosing

Many difficulties rhetoric, hyperreflexia, epileptic convulsions, sincopirovannam respiratory oliguriei, collapse, coma.

Precautions

There is a need to monitor the level of lithium in the blood (at least once per month). Furthermore, it should be immediately determine lithium manifestations of intoxication repeat diseases, changes salt exchange.

Dosing and Administration

Inside, at the time of delivery, not liquid, squeezed water or milk, as a rule, 1 g / day one (better morning), or 2 g / day divided into two doses (morning and evening). The level of lithium in the blood should be maintained within 0.6-1 mmol / l (the children 0.5-1 mmol / l). The dose of 1 g / day can be expected to stabilize in the 10 to 14 days of admission.

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