Bupranala injection 0.03%

Roman name

Solutio Bupranali pro injectionibus 0.03%

The composition and the form of

1 ml injection of buprenorphine 0.3 mg; USD in 1 ml, in a package of five vials or spric-tubikah to 1.3 ml, in a package spric-tubika 2.

Characteristics

Polusinteticescoe derivative of thebaine.

Of drugs

Blood drug (opioid analgethick). Is partial opioid agonist "mu" receptors.

Pharmacokinetics

Effects develops over 15-30 minutes (with the / m and / introduction), and continues 6-8 pm

Farmakodinamika

And higher analgeticescoy activity compared with morphine (about 30 times), to a lesser degree than morphine, it is addictive and therapeutic Zawisimosti.sposoben oppress breathing center, improves tone smooth muscles of internal organs.

Indications

Expressed severe pain syndrome of different etiology in oncology, trauma, cardiology, neurology, anaesthesiology and resuscitation, surgery (in aftercare period), first aid and emergency medical assistance.

Contraindications

Pregnancy, child. Absolute contraindication not.

Side-Effects

Drowsiness, dizziness, headache, sedative effect, sweating, demotion AD decrease pulmonary ventilation (in aftercare period), nausea, constipation, the delay urination.

Patient interaction

Together with the use of MAO inhibitors may develop malignant gipertermii, coma, hypertension, with the central nervous system depressants increased depressive action on Zns.polnae opioid agonists decrease analgesic effect and provoke withdrawal Sindrom.vozmojna between one sprite with diazepam and lorazepam.

Precautions

Be wary appoint patients with impaired lung, liver and kidney, older people with miksedema gipertireoidizmom and with the lack of BGs napochechnikov under oppression CNS, toxic psihozah, hyper prostate, the urethra stricture, dysfunction biliarnogo tract.

Dosing and Administration

V / m or / in slowly. Under adult dose-1-2 ml, re-introduction of the 6-8 h (with необходимости).Максим альная daily intake 1.8 Mg.u older patients, with the risk factors (diseases of the respiratory system, oppression CNS early aftercare period) dose reduced twice.

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