Mst continus

Roman name

MST Continus

The composition and the form of

1 tablet (with the controlled release of the active substance) contains morphine sulfate 10, 30, 60, 100 or 200 mg; blistere in 20 pcs. , in box 1 blister.1 tablet-10, 30, 60 or 100 mg; in a container 2000 st.1 capsule prolonged action-30, 60, 120 or 200 mg; blistere in 14 pcs. , in a box two blister.1 bag with pellets preparation prolonged suspension of the 20, 30, 60, 100 or 200 mg; per bundle 15 double sashe.1 suppository rektalny-30, 60, 100 or 200 mg; in the stripe 6 pcs. , in box 4 strip.

Of drugs

Analgezirutee. Waismann institute CNS receptors.

Pharmacokinetics

After intake of rapidly absorbed. The controlled release morphine from drug forms therapeutic level in the blood plasma is maintained for 12 hours

Clinical pharmacology

Galvanic effect of ingestion and Rectal Introduction develops in 30-40 min and continued for 12 hours (24 hours for capsules).

Indications

Expressed pain syndrome (stage III cancer, posleoperazionny period, etc.).

Pregnancy and lactation

Contraindicated in pregnancy. At the time of treatment should stop breastfeeding.

Contraindications

Hypersensitivity, respiratory depression, obstructive diseases of the respiratory system, eye slowdown stomach paralysis intestinal occlusion, acute kidney disease and psoriasis ways simultaneous MAO inhibitors and the two-week period after the end of the event's age to 7 years (for the treatment of postoperative pain syndrome), pregnancy, breast-feeding.

Side-Effects

Nausea, vomiting, bowel atony (up to development paralysis intestinal obstruction), constipation, tolerance, drug dependency.

Patient interaction

Do effects of tranquilizers, anesthetics, abused and sedated. When combined with MAO inhibitors may commencement or braking central to the emergence of hypermarkets and gipotenziveh krizov.

Overdosing

Symptoms : narrowing missed, oppression breathing centre gipotenzia; In severe cases, circulatory failure, Koma.lechenie : naloxone, in / in 0.4 mg, if necessary, again at intervals of 2-3 minutes or in the form of infusions-2 mg in 500 ml of physiological solution; Wash stomach, artificial respiration, the maintenance of the level of the liquid and electrolytes.

Precautions

The lower dose of depleted weakened and older patients, patients with gipertireoidizmom, chronic liver disease and kidney disease. Gently used in the mid vnutricerepnom pressure, as well as 24 hours before and during the first 12 h after operation. When driving should take into account the possible effect of attention.

Dosing and Administration

Doses picked individually depending on the extent controlling pain, age and Ballogo.tabletki : inwards with liquid, squeezed water every 12 hours Adults, the initial dose of 30 mg, if necessary, up to 60 mg unchanged interval between meals; Children - 0.2 mg / kg In aftercare bolevom syndrome (12 h after the operation), an adult weighing up to 70 kg to 20 mg, over 70 kg to 30 mg every 12 C.capsula : inwards once per day, at the same time, squeezed water (if not glotania contents of the capsules can be mixed with soft food). Granules preparation suspension : inside, the contents of bags add to the 10 (for the preparation of the suspensions contents bag 20, 30 and 60 mg), 20 (for the bag 100 mg), or 30 ml (for the bag 200 mg) water carefully removed and immediately go from warm (if the granules left in a glass, add a small amount of water, and mixed drink), the interval between meals 12 C.suppositorii : rektalno tentatively clearing intestine. Adults, the initial dose of 30 mg every 12 hours

Storage conditions

gran.d / susp. for the reception inside : When temperature is not above 25 ° Ckaps. : When temperature is not above 25 ° Csupp.rekt. : When temperature is not above 25 ° Ctabl. : When temperature is not above 25 ° C

Shelf life

gran.d / susp. for the reception inside : 2 g.kaps. : 3 g.supp.rekt. : 3 g.tabl. : 5 years

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