Nalorphine

Chemical name

(5альфа,6альфа)-7,8-Дидег идро-4,5-эпокси-17-(2-проп енил)морфинан- 3,6-diol (and as hydrochloride)

Gross

C19-H21-N-O3

Characteristics

White or white with a slightly yellowish white crystalline powder, dark in the air and light. Easily soluble in water, it is difficult to ethanol.

Of drugs

Drugs, the blocking Waismann receptors. Is агонистом/антагонист��м opioid receptors. Antagonistic effect is a decrease in analgeticski effects of morphine and its analogs weakening caused by the depressed respiration and reducing AD prevention of heart rhythm changes and the smooth muscle layer. Waismann stirring receptors is weak analgesic Effect.effect after injecting a 3-4 hrs

Indications

Overdosing narcotic analgesics or increased sensitivity to them (sharp respiratory depression and other abnormalities in the body).

Contraindications

Гиперчувствительност ь.

Side-Effects

Headache, mental institution, the alarming state, hallucinations, nausea, drowsiness, stalemate, failure, liver, skin, the gravity in the legs, alternating sense heat and cold.

Specific guidance

There used to treat morfinizma (possibly symptoms abstinence). Ineffective in cases of respiratory depression and circulatory disorders caused by barbituratami, ziklopropanom, ethyl ether.

Dosing and Administration

In / in, in / m or m / to the 0.005-0.01 g (1 ml of 0.5% solution). If necessary, repeat injections with intervals of 10-15 minutes. The total dose should not exceed 0.04 grams (8 ml of 0.5% раствора).Новорожденн ым in pupocnuu suicide on 0,0001-0,00025 g (0.2-0.5 ml of 0.5% solution), if necessary, re-injection at intervals of 1-2 minutes; total dose should not exceed 0.0008 and

Directory → Neurotropic funds → Opioids, their analogues and antagonists → Nalorphine