Prosidol

Chemical name

1-(2-Этоксиэтил)-4-фенил- 4-пропионилоксипипери дина hydrochloride

Characteristics

White with weak yellow white crystalline powder. Easily soluble in water.

Of drugs

The drugs-analgezirutee (drug). Applies to analgesics, agonistam opioid receptors. Activates antinozizeptivuyu system modifies emotions pain. Enlisting the opioid receptors in the blood leads to muscle relaxation intestine casings. At sfinktera influence is not. Stirring season segment glazodwigatelnogo nerve, it is failure. Provides aguirutee impact on the emetic and Setback for kashlevy centres. And tokoliticski action. Well drawn in any kind introduction. Connection with the plasma protein-40%. Treated biotransformation in the liver with the formation of inactive glukoronizirovannah metabolites. Excreted, mainly as a tribute in the form of metabolites, and the active form. The effect is as 15-30 minutes after the / m introduction and lasted until 4 pm The effect of pain weaker morphine.

Indications

Pain syndrome and myocardial infarct and acute pankreatite, colica renal, hepatic kolica, as a component of an integrated pain, mild pain in aftercare period pain syndrome in cancer patients expressed syndrome any genesis.

Restrictions on the use of

Pregnancy. There is no information on the safe use of the breast-feeding women and children.

Contraindications

Hypersensitivity, renal and hepatic failure, coma, alcohol intoxication, arterial hypotension, organic diseases of the central nervous system, epilepsy and convulsions tonico-clauniceskie in history, bronchial asthma, respiratory distress.

Side-Effects

Adjust, drug dependence syndrome "lifting", respiratory depression, convulsions, narcolepcia, arterial hypotension, aetiology, atony bowel and bladder, nausea, vomiting, liver failure and kidney amenorea, reduced libido, allergies, pain and redness at the injection.

Patient interaction

Do doses of tranquilizers, sleeping, alcohol, gipotenziveh funds. Naloxone and naltrexone are specific antagonists preparation.

Dosing and Administration

Adults give / m, / in, c / to the 5-10 mg (0.5-1 ml of 1% solution), in some cases, might be to GHG ml of 1% solution. Bukkalno 10-20 mg, inwards to 25 mg. Daily dose to 250 mg.

Directory → Neurotropic funds → Opioids, their analogues and antagonists → Prosidol