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Tramal 50

See also Tramadol

Roman name

Tramal 50

The composition and the form of

1 suppository containing tramadol hydrochloride 100 mg; in blistere 5 pcs. , in box blister.1 1 ml (40 drops) solution for the reception inside-100 mg; in vials to 10 or 96 mle.1 capsule 50 mg; blistere in 10 pcs. , in the box two blister.1 ml 13b3 solution for injection 50 mg; USD in 1 or 2 ml, in a Box 5 st.1 tablet coated liner retard 100 mg; blistere in 10 pcs. , in box 1, or 3 blisters.

Pharmacokinetics

Once inside absorbed more than 90% of dose bioavailability-68%, after rectal - slightly higher (79%). C_max achieved in 2 hours; C_max Tramala retard through 4-5 hours Linking blood protein 20% T_1/2 of plasma-6900, active metabolita 6.7 hours Metabolised in the liver, excreted (in the form of constant and in the form of metabolites) in the kidneys-90%, with spread-10%. Penetrates through the placental barrier (up to 80%) and in the mother's milk (0.1%).

Indications

Acute and chronic pain (severe and moderate) : In surgery, obstetrics, oncology, rheumatology, orthopedics, after dental interventions in neurology, and myocardial infarct, Cerebral lower limbs, etc.

Pregnancy and lactation

Only strict grounds.

Contraindications

Hypersensitivity, intoxication of alcohol, drugs, analgezirutmi or other means, oppressive CNS, the syndrome of "lifting" of drugs, up to 1 year (r-r NBSAPs. , R-r d / in.), or up to 12 years (supp., caps). And 14 years (tabl.retard).

Specific guidance

Solution tramadol should not be confused with one sprite Solutions diclaufenaka, indometacin, fenilbutazon, diazepam, flunitrazepama, glitzeriltrinitrata.

Patient interaction

Incompatible with MAO inhibitors. Do (mutually) effect of tranquilizers, sleeping, alcohol and other substances, oppressive central nervous system. Carbamazepine relaxed.

Precautions

During treatment should refrain from accepting alcohol and the truck and mechanical equipment (changing the reaction rate).

Storage conditions

List B. In a dry, the dark place at a temperature of 10-25 ° C

Shelf life

5 years

The registration

012128/01-2000

All products of this group

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