Suksilep

Roman name

Suxilep

Pharmacokinetics

Good concentration in the blood plasma of 100 µ g / J Metabolised in the liver, kidneys displayed (up to 20% in an unmodified form). T_1/2 adults-p 56-60, the children at 30-36 During the four-hour kidney from the body displayed 39-52% of the doses.

Indications

Small epileptic seizures : piknolepticalkie absansa, complex or atypical apnoea seizures, миоклонико-астатичес��ие small seizures (petit mal), youth mioclauniceskie seizures (impulsive small seizures).

Pregnancy and lactation

Is not recommended in pregnancy. At the time of treatment should stop breastfeeding.

Contraindications

Hypersensitivity, violations of the liver and / or kidneys, blood disease, porphyria.

Patient interaction

Carbmazepin accelerates etosximida withdrawal from the blood plasma, derivatives valproeva acid alter metabolism and plasma concentration (increase or decrease) etosximida. PP, deprimirotee CNS reinforce effect on the central nervous system. Decreases galoperidola concentration in plasma. Do not change the plasma levels primidona and phenobarbital may increase difenina concentration in plasma.

Precautions

There is a need to apply caution in patients with human psychological disorder. Patients in gemodialise, it is necessary to increase dose or change regimens. It should not be used in conjunction with the drivers of vehicles and people skills relate to the high concentration, as well as to exclude alcohol. When symptoms mielotoksicski possible actions (fever, tonzillit, increased bleeding) should see a doctor. In the case of pass receiving medication, missing dose compensate reception additional dose on the following day.

Dosing and Administration

Inside, during or after delivery, not liquid, squeezed enough liquid. Dose is a case-by-case basis, depending on the clinical picture, the individual patient response to PP and endurance. The total daily intake in adults and children 5 to 10 mg / kg body weight, with a gradual increase of 5 mg / kg every 4-7 days (stable level in the blood is achieved over a period of 8-10 days). The maximum daily intake of children - 40 mg / kg supporting-20 mg / kg in adults-30 mg / kg and 15 mg / kg, respectively.

Storage conditions

List B. The temperature is not above 25 ° C

Shelf life

5 years

The registration

013730/01-2002

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