Feprosidnine

Chemical name

3-(альфа-Метилфенетил)��иднонимин (as hydrochloride)

Gross

C11-H13-N3-O

Characteristics

White or white with weak yellowish sheen melkochristalliceski powder, odourless, bitter taste. Easily soluble in water, soluble in alcohol.

Of drugs

The drugs-psihostimulirutee, antidepressant. Provides indirect adrenomimeticescoe Effects : allows the release of presinapticakih endings and blocks reverse takeover norarenalina (mostly), and release. Increases adrenoretseptorov sensitivity to endogenous stimulation in the central nervous system (mainly) on the periphery. Psihostimuliruty effect combined with a moderate antidepressive activity (ingibiruet reversible MAO). Is antiholinergicakie properties. Quick thinking processes, eliminates drowsiness and fatigue, increases motor activity. Psihostimuliruty effect manifests itself in patients, and healthy people who are not accompanied by irritability, motor excitation. Decreases deprimirote effects rezerpina increases the epinephrine and norepinephrine, a modest increase Ad.bystro drawn from the blood, crosses the GEB, biotransformiroetsa in liver, presented with urine. Cumulative properties were found.

Indications

Asthenic of different genesis accompanied by adinamiei, electricity, podavlennostew, apathy and nervousness, diseases endocrine glands (hypothyroidism, addisonizm etc.), after over neiroinfection injuries and brain; Narcolepcia; Pathological fatigue; Simple depression, depression events sunk in the ticlotimii.

Contraindications

Hypersensitivity, тревожно-депрессивны�� condition, including the маниакально-депресси��ном psychosis, inwalutini depression, schizophrenia (possibly increased anxiety, increased �аллюцинаторно-бредов ого syndrome).

Side-Effects

Headache, dry mouth, increased AD pain in the heart, allergic reactions (skin); In rare cases, the paradoxical reaction (sedative effect).

Patient interaction

Incompatible with antidepressants, MAO inhibitors, and tricyclic antidepressants (a break of not less than 1 hour). Do adrenomimeticalkie effects of ephedrine and альфа-адреномиметико�� (under tremendous upsurge AD). Ters side effects of tranquilizers (drowsiness, miorelaxation). Decreases dampening effect on the central nervous system hypnotics and narcotic analgesics.

Dosing and Administration

Inside (before delivery, in the morning), the initial dose of 5 mg 1-2 times a day, if necessary, increase the dose of 5 mg / day every 2-3 days to 20-30 mg / sut. When a therapeutic effect dose gradually reduced. Supporting dose (if necessary long-term care insurance), 5 mg / Sut.pri heavy Pichinde states may raise dose to 80 mg / day (hospital).

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