Apo-flurazepam

Roman name

Apo-Flurazepam #

The composition and the form of

1 capsule contains flurazepama hydrochloride 15, or 30 mg; Patients in the 100 and 1,000 pcs.

Of drugs

Anxiolytic, sleeping. Prosecutor benzodiazepinove receptors and increases Gamkergicakie mezhneironne contacts.

Pharmacokinetics

Well drawn. The blood is not only a few hours, as quickly metabolized. Its main metabolite (desalkilflurazepam) has T_1/2 - 47-100 hours

Clinical pharmacology

1,657,700 sleep period, reducing probujdeni.

Indications

Violations of sleep (sleep difficulty, night awakening, early awakening).

Pregnancy and lactation

Not recommended during pregnancy and lactation.

Contraindications

Гиперчувствительност ь (including from other benzodiazepine derivatives), breathing problems as a result of oppression respiratory centre (including asthma patients in a dream), the paradoxical reaction to the alcohol and / or sedation, Children and Youth age (up to 18 years).

Side-Effects

Violation of memory, thinking, concentration, mental changes, depression, anxiety, weakness, dizziness, headache, drowsiness, ataxy, pain in the chest, pain in the heart, heart; Pain in the stomach and / or intestines, nausea, vomiting, diarrhea, constipation; Dizuriceskie phenomenon.

Patient interaction

Do devastating effect on the central nervous system antigistaminnah, psychotropic drugs and alcohol. Preparations ingibirute liver enzymes (zimetidin, erythromycin) increased activity Apo-flurazepama.

Overdosing

Symptoms-increasing side effects. Treatment-washing stomach, symptomatic therapy.

Precautions

Be wary appoint patients suffering from chronic alcoholism and mental disorders (possibly of Drug Dependence), and depression (possibly increased symptoms), human liver and kidneys, in old age. During treatment should refrain from activities that require greater attention and rapid mental and motor reactions. Avoid abrupt cancellation of the drug and reduce the dose gradually.

Dosing and Administration

Inside, at night. Adults, 15-30 mg, the elderly and immunocompromised patients start with 15 mg. The duration of treatment is 10 days.

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