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IvadalSee also ZolpidemRoman nameIvadalThe composition and the form of1 tablet coated liner delimaya contains zolpidem tartrate 10 mg; blistere in 1910 or 7 pc. , in box 2 or 1 blister respectively.PharmacokineticsRapidly absorbed from the digestive tract. Bioavailability of 70% (subject to presistemnomu metabolizmu). C_max achieved through sunbathing and Linking plasma protein-92.5%. T_1/2 2.4 h, the duration of the six-hour Place in the form of active metabolites in the urine (56%) and faeces (37%).FarmakodinamikaIn therapeutic doses shortened sleep time, and reduces the number of night probujdeni increases the length (lengthens stage II-IV) sleep and improves its quality.IndicationsViolations of sleep : difficulty sleep, night awakening, situational, short-term and chronic sleep disturbance.Pregnancy and lactationCont 596 raindicated. At the time of treatment should stop breastfeeding.ContraindicationsHypersensitivity, patients in a dream expressed infants, severe respiratory or liver failure, pregnancy, breast-feeding, child age (up to 15 years).Side-EffectsRarely, drowsiness, headache, dizziness, gait violation, the institution (or the night after stopping treatment), sputannosti consciousness, the memory (anterogradnaya amnesia), visual distress perception, nightmares; Pain in the abdomen, nausea, vomiting, diarrhoea, skin rashes, itching of the skin; In the long-term it is the development of dependence.Patient interactionDo (mutually) effect other funds oppressive CNS; Incompatible with alcohol.PrecautionsThe development of side effects to the lack of sleep, the use in doses much higher than recommended, long continuous use, combined with benzodiazepines. Be wary appoint patients with re 8c5 spiratory or liver failure, myasthenia. It should not be used in conjunction with the drivers of vehicles and people skills relate to the high concentration of attention.Dosing and AdministrationInside, just before bedtime, one dose is individually. For patients under 65 years, usually 10 mg; Patients over 65 years of age, 5 mg, if necessary, no more than 10 mg. Duration of treatment : seetuatinaya insomnia from one reception to 2-5 days; Short - 2-3 weeks, but not more than four weeks; Chronic, the only doctor.Storage conditionsList B. At temperatures below 25 ° CShelf life4The registration014944/01-2003 |
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